Results 41 to 50 of about 88,198 (304)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Dynamic Shear Deformation in Zinc Crystals [PDF]
, 1962 The initial stages of yielding in single crystals of zinc have been investigated at temperatures of -292°F (-180°C), -93°F (-70°C) and +75°F (24°C), by means of rapidly applied constant stress pulses to produce slip along the basal planes of these ...
King, Kenneth Robert
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
A unified model for dislocation nucleation, dislocation emission and dislocation free zone
, 1996 In this paper, a unified model for dislocation nucleation, emission and dislocation free zone is proposed based on the Peierls framework. Three regions are identified ahead of the crack tip.
张永伟 +3 more
core +1 more source
Plastic flow and dislocation strengthening in a dislocation density based formulation of plasticity
, 2021 S.317-327Modeling dislocation interaction on a mesoscopic scale is an important task for the description of flow stress and strain hardening in a continuum model.
Schulz, K., Gumbsch, Peter, Sudmanns, M.
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Проблеми трибологіїBased on an investigation of how entropy generation depends on material and tribological characteristics, it was found that the wear rate of a sliding bearing operating under elastic and elastoplastic contact conditions exhibits a nonmonotonic ...
O. Shchukin +4 more
doaj +1 more source
Semiconductor Physics, Quantum Electronics & Optoelectronics, 2016 In this paper, different methods for lowering the dislocation density such as incorporation of the buffer layers, substrate patterning and nitridation, silan-ammonia treatment are reviewed and compared. Advantages and limitations of these methods as well
P.V. Parphenyuk
doaj +1 more source
On Mathematical Aspects of Evolution of Dislocation Density in Metallic Materials
IEEE Access, 2022 This paper deals with the solution of delay differential equations describing evolution of dislocation density in metallic materials. Hardening, restoration, and recrystallization characterizing the evolution of dislocation populations provide the essential equation of the model.
Natalia Czyzewska +7 more
openaire +3 more sources
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source