Results 111 to 120 of about 346,257 (357)

From De Novo Conceived Small Molecules to Multifunctional Supramolecular Nanoparticles: Dual Biofilm and T3SS Intervention, Enhanced Foliar Affinity, and Effective Rice Disease Control

open access: yesAdvanced Science, EarlyView.
From de novo engineered bioactive molecules BtP27 to the multifunctional supramolecular material BtP27@β‐CD with a sunflower‐shaped morphology: its pragmatic applications in augmenting foliar affinity, disrupting biofilms and T3SS, and managing rice pathologies. Abstract Conventional antimicrobials typically exhibit suboptimal deposition on rice leaves,
Xianfu Mu   +6 more
wiley   +1 more source

Manganese Superoxide Dismutase Overexpression Attenuates MPTP Toxicity

open access: yesNeurobiology of Disease, 1998
There is substantial evidence implicating mitochondrial dysfunction and free radical generation in the neurotoxicity of MPTP. Manganese superoxide dismutase (MnSOD) is the primary antioxidant enzyme protecting against superoxide radicals produced within ...
Peter Klivenyi   +6 more
doaj  

Antioxidant Activity of SOD and Catalase Conjugated with Nanocrystalline Ceria

open access: yesBioengineering, 2017
Interactions of nanoparticles with biological matter—both somatically and in nature—draw scientists’ attention. Nanoparticulate systems are believed to be our saviors, acting as versatile drug delivery vehicles.
Dmitry Gil   +5 more
doaj   +1 more source

Tumour suppressor SIRT3 deacetylates and activates manganese superoxide dismutase to scavenge ROS

open access: yesEMBO Reports, 2011
Mitochondria manganese superoxide dismutase (SOD2) is an important antioxidant enzyme, deficiency of which is associated with various human diseases. The known primary regulation of SOD2 is through transcriptional activation. Here, we report that SOD2 is
Yaohui Chen   +6 more
semanticscholar   +1 more source

Orally Administered Functional Polyphenol‐Nanozyme‐Armored Probiotics for Enhanced Amelioration of Intestinal Inflammation and Microbiota Dysbiosis

open access: yesAdvanced Science, EarlyView.
This study presents a novel polyphenol‐nanozyme‐armored probiotic system (ECA@EcN) for enhanced treatment of inflammatory bowel disease (IBD). By integrating chitosan‐modified epigallocatechin gallate (EGCG‐CS) with gold nanozymes, the system effectively scavenges ROS, improves probiotic viability, and restores gut microbiota balance.
Yong Zhu   +12 more
wiley   +1 more source

Simultaneous Monitoring of Tyrosinase and ATP in Thick Brain Tissues Using a Single Two‐Photon Fluorescent Probe

open access: yesAdvanced Science, EarlyView.
A single dual‐emission two‐photon fluorescent probe is designed for simultaneously tracking tyrosinase (TYR) and adenosine triphosphate (ATP). With the help of this probe, the intricate correlation and regulatory mechanism between TYR and ATP during oxidative stress is uncovered.
Hong Huang   +12 more
wiley   +1 more source

SENP3 Drives Abdominal Aortic Aneurysm Development by Regulating Ferroptosis via De‐SUMOylation of CTH

open access: yesAdvanced Science, EarlyView.
In this study, it is proposed that SENP3 accumulates in macrophages of aneurysmal aortic tissues, which promotes macrophage ferroptosis and inflammation via regulation of CTH de‐SUMOylation. Abstract Abdominal aortic aneurysm (AAA) is a high‐risk inflammatory disorder. SENP3, a SUMO2/3‐specific protease, is closely involved in the development of cancer.
Long Chen   +15 more
wiley   +1 more source

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