Results 131 to 140 of about 346,257 (357)

Implanted Microneedles Loaded with Sparfloxacin and Zinc‐Manganese Sulfide Nanoparticles Activates Immunity for Postoperative Triple‐Negative Breast Cancer to Prevent Recurrence and Metastasis

Advanced Science, EarlyView.
Hyaluronic acid Microneedles (MNs) are loaded with Sparfloxacin (SP) and zinc‐manganese sulfide (ZMS) for the postoperative in situ treatment of triple‐negative breast cancer (TNBC) to prevent cancer recurrence and combat wound infection. These microneedles enhance antitumor immunity by activating the cGAS‐STING pathway, suppress tumor growth, reduce ...
Zhaoyou Chu, Wang Zheng, Wanyue Fu, Jun Liang, Wanni Wang, Lingling Xu, Xiaohua Jiang, Zhengbao Zha, Haisheng Qian   +8 more
wiley   +1 more source

Predictive biomarkers for 5‐ALA‐PDT can lead to personalized treatments and overcome tumor‐specific resistances

Cancer Reports, Volume 5, Issue 12, December 2022., 2022
Abstract Background Photodynamic therapy (PDT) is a minimally invasive, clinically approved therapy with numerous advantages over other mainstream cancer therapies. 5‐aminolevulinic acid (5‐ALA)‐PDT is of particular interest, as it uses the photosensitiser PpIX, naturally produced in the heme pathway, following 5‐ALA administration.
Maria Mastrangelopoulou, Mantas Grigalavicius, Tine H. Raabe, Ellen Skarpen, Petras Juzenas, Qian Peng, Kristian Berg, Theodossis A. Theodossiou   +7 more
wiley   +1 more source

Labile Sulfur in Human Superoxide Dismutase [PDF]

, 1975
Lilia Calabrese, Giorgio Federici, Giuseppe Rotilio, Alessandro Finazzi‐Agrò, W.H. Bannister, Joseph V. Bannister   +5 more
openalex   +1 more source

Improved Orthogonality in Naphthalimide/Cyanine Dyad Boosts Superoxide Generation: a Tumor‐Targeted Type‐I Photosensitizer for Photodynamic Therapy of Tumor by Inducing Ferroptosis

Advanced Science, EarlyView.
A tumor‐targeted, renal‐metabolized, and less O2‐dependent Type‐I photosensitizer is presented for photodynamic therapy of tumors. The formation of an intramolecular sandwich‐like π–π assembly ensures its rigid orthogonal geometry, thereby improving the superoxide (O2•−)‐generating ability, promoting the intracellular formation of hydroxy radical (HO•),
Guangxiao Yao, Junfeng Miao, Yingying Huo, Wei Guo   +3 more
wiley   +1 more source

Molecular and cellular paradigms of multidrug resistance in cancer

Cancer Reports, Volume 5, Issue 12, December 2022., 2022
Abstract Background The acquisition of resistance to chemotherapy is a major hurdle in the successful application of cancer therapy. Several anticancer approaches, including chemotherapies, radiotherapy, surgery and targeted therapies are being employed for the treatment of cancer.
Foram U. Vaidya, Abu Sufiyan Chhipa, Vinita Mishra, Vishal Kumar Gupta, Shiv Govind Rawat, Ajay Kumar, Chandramani Pathak   +6 more
wiley   +1 more source

Determination of oxidative stress level and some antioxidant activities in refractory epilepsy patients

Scientific Reports
The aim of this study was to determine the levels of superoxide dismutase (SOD), catalase (CAT), reduced glutathione (GSH) and malondialdehyde (MDA) in patients with refractory epilepsy.
Abdullah Yilgor, Canan Demir
doaj   +1 more source

CO‐Releasing Polyoxometalates Nanozyme with Gut Mucosal Immunity and Microbiota Homeostasis Remodeling Effects for Restoring Intestinal Barrier Integrity

Advanced Science, EarlyView.
A CO‐releasing polyoxometalates nanozyme (PMC) is engineered by coordinating pentacarbonyl manganese bromide with molybdenum‐based polyoxometalates nanoclusters. PMC exhibits targeted accumulation at IBD sites, efficient ROS scavenging, and responsive CO release.
Hongyang Lu, Qiang Zhou, Jiayu Li, Shengming Xu, Li Yu, Yinci Zhu, He Zhang, Chengge Shi, Tianci Zuo, Mengzhu Xu, Mingli Su, Yanmei Zhang, Rongdang Hu, Quazi T. H. Shubhra, Hui Deng, Xiaowen Hu, Xiaojun Cai   +16 more
wiley   +1 more source

The Encapsulation Strategies for Targeted Delivery of Probiotics in Preventing and Treating Colorectal Cancer: A Review

Advanced Science, EarlyView.
This work summarizes the efficacy and mechanisms of probiotics in CRC treatment, providing a comprehensive overview of various encapsulation methods such as microcapsules, hydrogels, single‐cell nanocoatings, and nanofibers for targeted probiotic delivery to inflammatory sites, with particular emphasis on the potential advantages of emerging single ...
Hao Zhong, Jin Jiang, Muhammad Hussain, Haoxuan Zhang, Ling Chen, Rongfa Guan   +5 more
wiley   +1 more source

Superoxide dismutase activity of low molecular weight Cu²⁺‐chelates studied by pulse radiolysis [PDF]

, 1974
Regina Brigelius, Rita Spöttl, Wolf Bors, Edmund Lengfelder, Manfred Sarán, Ulrich Weser   +5 more
openalex   +1 more source