Results 141 to 150 of about 346,257 (357)

Optimization of Lipid Nanoparticles with Robust Efficiency for the Delivery of Protein Therapeutics to Augment Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
This study develops lipid nanoparticles (LNPs) combining cationic and ionizable lipids for efficient cytosolic protein delivery. Optimized LNPs deliver functional proteins, including antibodies, enzymes, and Cas9, with high serum stability and albumin‐mediated endocytosis.
Lanfang Ren   +6 more
wiley   +1 more source

Robust Controlled Degradation of Enzyme Loaded PCL‐Based Fibrous Scaffolds Toward Scarless Skin Tissue Regeneration

open access: yesAdvanced Science, EarlyView.
A novel biodegradable wound dressing (E‐PCLs) based on polycaprolactone (PCL) and an enzyme complex (RHP‐BCL) is developed using a fiber microfluidic electrospinning technique. The dressing achieves complete degradation within 14 days, eliminates microplastic residues, and promotes scar‐free healing (99% in 21 days).
Lingling Fan   +7 more
wiley   +1 more source

An update and review of narrowband ultraviolet B phototherapy for vitiligo

open access: yesDermatological Reviews, Volume 3, Issue 5, Page 326-335, October 2022., 2022
Abstract Vitiligo is a chronic skin condition that results in depigmentation. It affects up to 2% of the population worldwide. Phototherapy is one of the most commonly used treatment methods for vitiligo. In the last few decades, there has been an increasing popularity of narrowband ultraviolet B phototherapy (NB‐UVB) over other forms of phototherapy ...
Eugene Wang, Michelle Rodrigues
wiley   +1 more source

Superoxide dismutase and glutathione peroxidase activities in tumors [PDF]

open access: bronze, 1977
Alexander V. Peskin   +2 more
openalex   +1 more source

Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein).

open access: yesJournal of Biological Chemistry, 1969
J. McCord, I. Fridovich
semanticscholar   +1 more source

Mechanical Biomimetic Nanocomposites for Multidimensional Treatment of Arterial Thrombosis

open access: yesAdvanced Science, EarlyView.
In this study, a mechanical biomimetic nanocomposite is developed, guided by photoacoustic imaging, to achieve highly efficient and safe thrombolysis through the synergistic effects of photothermal therapy and pharmacological intervention. Most notably, the nanoparticle improves the microenvironment of arterial thrombi, marked by high shear stress and ...
Ying Li   +6 more
wiley   +1 more source

Functional consequences of brain exposure to saturated fatty acids: From energy metabolism and insulin resistance to neuronal damage

open access: yesEndocrinology, Diabetes &Metabolism, Volume 6, Issue 1, January 2023., 2023
Saturated fatty acids induce insulin resistance in neurons. Neuronal metabolism of palmitic acid alters mitochondrial function. Abstract Introduction Saturated fatty acids (FAs) are the main component of high‐fat diets (HFDs), and high consumption has been associated with the development of insulin resistance, endoplasmic reticulum stress and ...
Karina Sánchez‐Alegría   +1 more
wiley   +1 more source

Endogenous Near‐Infrared Chemiluminescence: Imaging‐Guided Non‐Invasive Thrombolysis and Anti‐Inflammation Based on a Heteronuclear Transition Metal Complex

open access: yesAdvanced Science, EarlyView.
Cu2Ir NPs based on a Cu‐porphyrin core and cyclometalated Ir(III) substituents achieve combined endogenous peroxynitrite‐triggered NIR chemiluminescence imaging, PTT and PDT for successfully achieving safe thrombolysis, antioxidant and anti‐inflammatory multifunctionality in one single molecule.
Ziwei Wang   +13 more
wiley   +1 more source

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