Results 311 to 320 of about 346,257 (357)

SUPEROXIDE RADICAL AND SUPEROXIDE DISMUTASES

Annual Review of Biochemistry, 1972
O2- oxidizes the [4Fe-4S] clusters of dehydratases, such as aconitase, causing-inactivation and release of Fe(II), which may then reduce H2O2 to OH- +OH.. SODs inhibit such HO. production by scavengingO2-, but Cu, ZnSODs, by virtue of a nonspecific peroxidase activity, may peroxidize spin trapping agents and thus give the appearance of catalyzing OH ...
openaire   +5 more sources

Undetectable intracellular free copper: the requirement of a copper chaperone for superoxide dismutase.

Science, 1999
The copper chaperone for the superoxide dismutase (CCS) gene is necessary for expression of an active, copper-bound form of superoxide dismutase (SOD1) in vivo in spite of the high affinity of SOD1 for copper (dissociation constant = 6 fM) and the high ...
T. Rae, P. Schmidt, R. A. Pufahl, Valeria L Culotta, T. O’Halloran   +4 more
semanticscholar   +1 more source

Effect of aluminium on lipid peroxidation, superoxide dismutase, catalase, and peroxidase activities in root tips of soybean (Glycine max)

, 1991
Inhibition of root elongation and modification of membrane properties are sensitive responses of plants to aluminium. The present paper reports on the effect of AI on lipid peroxidation and activities of enzymes related to production of activated oxygen ...
I. Cakmak, W. Horst
semanticscholar   +1 more source

Superoxide dismutases in Eimeria tenella

Molecular and Biochemical Parasitology, 1991
Unsporulated oocysts of Eimeria tenella have high superoxide dismutase (SOD: superoxide:superoxide oxidoreductase, EC 1.15.1.1.) activity and contain several electrophoretically distinct forms of the enzyme, including two forms of Cu/Zn-containing SOD, two forms of Fe-SOD and two forms of Mn-SOD. SOD activity remains high during 12 h of sporulation but
Wojtek P. Michalski, Stephen J. Prowse
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Polarographic determination of superoxide dismutase

Analytical Biochemistry, 1975
Abstract A polarographic procedure is described which allows determination of the catalytic constants for superoxide dismutase-catalyzed reactions. The method presents a single and rapid evaluation of the enzyme concentrations as well as determination of its activity under different conditions; e.g., pH between 9 and 13, presence of urea, guanidine ...
Giuseppe Rotilio, A. Rigo, Paolo Viglino
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Bacterial superoxide dismutase and virulence

2002
[No abstract available]
Paul R. Langford, Assunta Sansone, VALENTI, PIERA, Andrea Battistoni, J. S. Kroll   +4 more
openaire   +6 more sources

Effect of Aluminium on Superoxide Dismutase

Clinical Science, 1989
1. The effect of Al3+ on superoxide dismutase in vitro was studied, since in uraemia there is excessive superoxide production and frequently an elevated serum Al3+ level. Thus, the protective role of superoxide dismutase is particularly important. 2.
Geoffrey M. Berlyne, Ruth Shainkin-Kestenbaum, C. Caruso, Andrew J. Adler   +3 more
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Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster.

Science, 1994
The hypothesis that oxygen free radicals are causally involved in the aging process was tested by a study of the effects of simultaneous overexpression of copper-zinc superoxide dismutase and catalase.
W. Orr, R. S. Sohal
semanticscholar   +1 more source

Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase.

Science, 1993
Single-site mutants in the Cu,Zn superoxide dismutase (SOD) gene (SOD1) occur in patients with the fatal neurodegenerative disorder familial amyotrophic lateral sclerosis (FALS).
H. Deng, A. Hentati, J. Tainer, Zafar Iqbal, A. Cayabyab, W. Hung, E. Getzoff, Ping Hu, B. Herzfeldt, R. Roos, C. Warner, Gang Deng, Edwin Soriano, C. Smyth, H. Parge, Aftab Ahmed, A. Roses, R. Hallewell, M. Pericak-Vance, T. Siddique   +19 more
semanticscholar   +1 more source

Microbial Superoxide Dismutases

1989
Publisher Summary The presence of oxygen in the environment presents both advantages and threat to all forms of life. The use of oxygen as a final electron acceptor provides more energy than that afforded by anaerobic fermentation. Oxygen is also useful in many biosynthetic reactions.
openaire   +2 more sources