Evolutionary relationships in superoxide dismutase [PDF]
Two distinct types of superoxide dismutase have been isolated from aerobic organisms. A blue-green Cu-Zn protein with a mol. wt of 32 000 and comprising two identical subunits has been obtained from a wide range of eukaryotes (e.g. [3,4]) while a pinkish-purple Mncontaining enzyme, also composed of identical subunits, has been isolated from eukaryotic ...
Fred Northrop+2 more
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Catalytically Potent and Selective Clusterzymes for Modulation of Neuroinflammation Through Single-Atom Substitutions [PDF]
Emerging artificial enzymes with reprogrammed and augmented catalytic activity and substrate selectivity have long been pursued with sustained efforts. The majority of current candidates rely on noble metals or transition metal oxides with rather poor catalytic activity compared with natural molecules.
arxiv +1 more source
Superoxide DismutasE in Spring Barley Caryopses
Superoxide dismutase (SOD) activity was determined in caryopses of spring barley grown in field trials in 2004–2006. A total set under study included five malting varieties with hulled grain, three waxy hull-less and hulled varieties (of US origin ...
Natálie Březinová Belcredi+1 more
doaj +1 more source
DFT Investigation of Biocatalytic Mechanisms from pH-Driven, Multi-Enzyme, Biomimetic Behavior in CeO2 [PDF]
There is considerable interest in the pH-dependent, switchable, biocatalytic properties of cerium oxide (CeO2) nanoparticles (CeNPs) in biomedicine, where these materials exhibit beneficial antioxidant activity against reactive oxygen species (ROS) at basic physiological pH but cytotoxic prooxidant activity in acidic cancer cell pH microenvironment ...
arxiv +1 more source
Increased peripheral lipid clearance in an animal model of amyotrophic lateral sclerosis [PDF]
Amyotrophic lateral sclerosis (ALS) is the most common adult motor neuron disease, causing motor neuron degeneration, muscle atrophy, paralysis, and death. Despite this degenerative process, a stable hypermetabolic state has been observed in a large subset of patients.
arxiv +1 more source
Synthesis and Antioxidant Activities of [5-fluoro N, N'-bis (salicylidene) ethylenediamine] and [3, 5-fluoro N, N'-bis (salicylidene) ethylenediamine] Manganese (III) Complexes [PDF]
Antioxidants act as free radical scavengers in the oxidation processes. Thus, they will certainly play diverse roles in the biological systems and the therapy of a wide variety of diseases.
Sakineh Meftah, Razieh Yazdanparast
doaj
Nickel superoxide dismutase protects nitrogen fixation in Trichodesmium
Trichodesmium, a major diazotroph in tropical and subtropical oceans, provides a significant amount of bioavailable nitrogen in oligotrophic oceans. Remarkably, the cyanobacteria carry out nitrogen fixation and photosynthesis simultaneously under high ...
Chih‐Chang Chen+7 more
doaj +1 more source
Superoxide dismutase in anaerobes: survey [PDF]
Superoxide dismutase (SOD) was present in 23 of 28 strains of the genus Bacteroides tested. Several clostridia, anaerobic cocci, and anaerobic, grampositive, nonsporing rods contained measureable SOD, but the frequency of SOD occurrence was much lower than in the bacteroides.
W E Moore, L V Holdeman, E M Gregory
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The trail to superoxide dismutase [PDF]
City College of New York + Cornell Medical School + Duke. While a youngster, I was enthralled by the miracle of insect metamorphosis and followed the transformations of pet caterpillars to pupae and then to gloriously beautiful butterflies and moths. This led naturally to an interest in biology. but mere description was not totally satisfying.
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Reaction Cycles of Halogen Species in the Immune Defense: Implications for Human Health and Diseases and the Pathology and Treatment of COVID-19 [PDF]
There is no vaccine or specific antiviral treatment for COVID-19. One current focus is drug repurposing research, but those drugs have limited therapeutic efficacies and known adverse effects. The pathology of COVID-19 is essentially unknown. It is therefore challenging to discover a successful treatment to be approved for clinical use.
arxiv +1 more source