Results 61 to 70 of about 346,257 (357)

High expression of antioxidant proteins in dendritic cells: possible implications in atherosclerosis [PDF]

open access: yesMol Cell Proteomics 5 (04/2006) 726-36, 2006
Dendritic cells (DCs) display the unique ability to activate naive T cells and to initiate primary T cell responses revealed in DC-T cell alloreactions. DCs frequently operate under stress conditions. Oxidative stress enhances the production of inflammatory cytokines by DCs.
arxiv   +1 more source

The Regulation of Trace Metal Elements in Cancer Ferroptosis

open access: yesAdvanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang   +5 more
wiley   +1 more source

Characterizing Isozymes of Chlorite Dismutase for Water Treatment

open access: yesFrontiers in Microbiology, 2017
This work investigated the potential for biocatalytic degradation of micropollutants, focusing on chlorine oxyanions as model contaminants, by mining biology to identify promising biocatalysts.
Kellen C. Mobilia   +2 more
doaj   +1 more source

The copper‐zinc superoxide dismutase activity in selected diseases

open access: yesEuropean Journal of Clinical Investigation, 2018
Copper‐zinc superoxide dismutase (Cu,Zn‐SOD) plays a protective role in various types of tissue protecting them from oxidative damage. Alterations in Cu,Zn‐SOD (SOD1 and SOD3) activity and its expression have been observed in pathological occurrences ...
Łukasz Lewandowski   +2 more
semanticscholar   +1 more source

Non‐Enzymatic Destruction of the Extracellular Matrix for Activatable Orthotopic Tumor Treatment and Enhanced Drug Penetration

open access: yesAdvanced Functional Materials, EarlyView.
Supramolecular biomimetic nanoaggregates (HFCu NAs), constructed with fluorinated histidine and copper ions via metal coordination and aromatic packing, exhibit enhanced reactive oxygen species (ROS)generation at tumor sites, which results in stepwise collapse of the extracellular matrix (ECM), affording tumor microenvironment responsive “turn‐on” 19F ...
Hui Wang   +8 more
wiley   +1 more source

The influence of cigarette smoking on blood and salivary super oxide dismutase enzyme levels among smokers and nonsmokers—A cross sectional study

open access: yesJournal of Traditional and Complementary Medicine, 2015
To determine the influence of smoking on blood and salivary superoxide dismutase enzyme levels among smokers, and to demonstrate the significant alterations in the levels of superoxide dismutase in association with patient age, periodontal disease status,
Haziel Diana Jenifer   +4 more
doaj   +1 more source

Mechanical probes of SOD1 predict systematic trends in metal and dimer affinity of ALS-associated mutants [PDF]

open access: yes, 2012
Mutations and oxidative modification in the protein Cu,Zn superoxide dismutase (SOD1) have been implicated in the death of motor neurons in amyotrophic lateral sclerosis (ALS), a presently incurable, invariably fatal neurodegenerative disease. Here we employ steered, all-atom molecular dynamics simulations in implicit solvent to investigate the ...
arxiv   +1 more source

Electric Pulse Regulated MXene Based Nanozymes for Integrative Bioelectricity Immuno‐Cancer Therapy

open access: yesAdvanced Functional Materials, EarlyView.
MXenzyme‐mediated bioelectricity cancer therapy (MXenzyme‐BECT) enhances cancer cell death through irreversible depolarization, ion channel disruption, ROS generation, and immunogenic cell death. Computational simulations reveal the electrical mechanisms by which MXenzyme acts on single cells and support to predict treatment parameters. Next‐generation
Sanghee Lee   +6 more
wiley   +1 more source

RNAlater facilitates remote sampling of aquaculture Atlantic salmon liver for proteomic analysis

open access: yesAquaculture, Fish and Fisheries, Volume 2, Issue 6, Page 578-586, December 2022., 2022
Graphical Abstract Proteomes of similar sizes were obtained in samples preserved by snap‐freezing or RNAlater. Proteins involved in transcriptional and translational machinery were affected in RNAlater stored samples. Abundance of published markers for heat and oxidative stress was not affected by snap‐freezing or RNAlater.
Anca G. Rusu   +6 more
wiley   +1 more source

Estimation Of Salivary Superoxide Dismutase Level In Oral Submucous Fibrosis: A Clinical And Biochemical Study

open access: yesJournal of Bahria University Medical and Dental College, 2019
Objective: The objective of the study was to compare the salivary Superoxide dismutase (mU/L) level among stage one patients of Oral sub mucous fibrosis and healthy controls.
Humera Akhlaq   +2 more
doaj   +1 more source

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