Results 111 to 120 of about 5,552,271 (346)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

The Impact of the COVID‐19 Pandemic on the Well‐Being of People With Borderline Personality Disorder: A National Australian Study

Mental Health Science
Social isolation due to the COVID‐19 pandemic was a significantly destabilizing factor for people with borderline personality disorder (BPD). The aim of this study was to investigate the well‐being of Australians diagnosed with BPD during the initial ...
Parvaneh Heidari, Jillian H. Broadbear, Marita Mohammadshahi, Farzaneh Foroughinia, Rita Brown, Sathya Rao   +5 more
doaj   +1 more source

Size-dependent structural and magnetic properties of disordered Co2FeAl Heusler alloy nanoparticles [PDF]

, 2018
Aquil Ahmad, Srimanta Mitra, S. K. Srivastava, A. K. Das   +3 more
openalex   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Early-life lead exposure and neurodevelopmental disorders

, 2021
Damaris Albores‐García, Jennifer L. McGlothan, Tomás R. Guilarte   +2 more
openalex   +2 more sources

A brief measure for assessing generalized anxiety disorder: the GAD-7.

Archives of Internal Medicine, 2006
R. Spitzer, K. Kroenke, Janet B W Williams, B. Löwe   +3 more
semanticscholar   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Navigating parenthood in people living with borderline personality disorder: a meta-ethnography

Borderline Personality Disorder and Emotion Dysregulation
Background Emotional dysregulation, impulsivity, and interpersonal difficulties are some of the severe and debilitating symptoms of borderline personality disorder (BPD). Parenting while living with BPD is associated with high levels of parental distress,
Karthika Kasiviswanathan, Jessica Lee, Sathya Rao, Jillian H. Broadbear   +3 more
doaj   +1 more source

Enhancing exciton diffusion by reducing energy disorder in organic solar cells

, 2022
Peiyao Xue, Adiel Calascibetta, Kai Chen, Karen E. Thorn, Yiting Jiang, Jiangjian Shi, Boyu Jia, Mengyang Li, Jingming Xin, Guilong Cai, Rui Yang, Heng Lu, Sara Mattiello, Yao Liu, Zheng Tang, Wei Ma, Xinhui Lu, Qingbo Meng, Justin M. Hodgkiss, Luca Beverina, Ray P. S. Han, Xiaowei Zhan   +21 more
openalex   +2 more sources