Results 121 to 130 of about 5,886,495 (367)

fNIRS-Based characterization of adolescent depression using dynamic functional connectivity biomarkers in a verbal fluency task

BMC Psychiatry
Background The human brain is a dynamic neural system with time-varying functional connectivity (FC) strengths between brain regions. Evidence indicates that adolescents with major depressive disorder (MDD) exhibit decreased average FC strength in ...
Tongxin Li, Yeqing Dong, Qingyan Jiao, Lijun Chu, Jianli Qiu, Yanlei Fu, Yongyan Gao, Zhonghui Ma, Xia Sun, Yong Zhang   +9 more
doaj   +1 more source

Disorder! Disorder! Disorder! [PDF]

Acta Crystallographica Section A Foundations and Advances, 2017
Christine M. Beavers, Theocharis Stamatatos   +1 more
openaire   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

Body image flexibility and embodiment in eating disorders: a mixed-methods approach combining network analysis and pilot exposure protocol

Journal of Eating Disorders
Objective Body image (BI) disturbances are central to the psychopathology of eating disorders (EDs), where body dissatisfaction and disembodiment often co-occur, exacerbating negative body image experiences. We aimed to examine body image flexibility and
Paolo Meneguzzo, Chiara Cazzola, Francesca Buscaglia, Anna Pillan, Filippo Pettenuzzo, Patrizia Todisco   +5 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Alcohol Use Disorder and Depressive Disorders

Alcohol research : current reviews, 2019
Alcohol use disorder (AUD) and depressive disorders are among the most prevalent psychiatric disorders and co-occur more often than expected by chance.
R. McHugh, R. Weiss
semanticscholar   +1 more source

Working towards an international consensus on criteria for assessing Internet Gaming Disorder: a critical commentary on Petry et al. (2014) [PDF]

, 2016
This commentary paper critically discusses the recent debate paper by Petry et al. (2014) that argued there was now an international consensus for assessing Internet Gaming Disorder (IGD).
Haagsma, Maria C., Derevensky, J., Kai Müller, Billieux, J., Carras, M., Daria J. Kuss, Joël Billieux, Nicole Prause, Michael Dreier, Coulson, M, Lopez-Fernandez, O, Rooij, A.J., Király, O., King, Daniel, Antonius J. van Rooij, Lopez Fernandez, O., Delfabbro, Paul, Ferguson, Christopher J, Hoff, Rani A, Kuss, Daria, Daniel Kardefelt‐Winther, Nagygyorgy, Katalin, Starcevic, Vladan, Billieux, Joël, Derevensky, Jeffrey, Griffiths, MD, Kuss, Daria J., Vladan Starcevic, Király, O, Paul Delfabbro, Orsolya Király, Király, Orsolya, Olatz Lopez Fernandez, Daniel L. King, Kuss, D.J., Aboujaoude, E, Starcevic, V., Ferguson, CJ, Hoff, R.A., Kuss, Daria J, Nagygyörgy, K, Pallesen, S, Fernandez, Olatz Lopez, Carbonell, Xavier, Ståle Pallesen, Billieux, J, Achab, Sophia, Prause, Nicole, Nagygyorgy, K., King, Daniel L, Pontes, Halley M, Carbonell, X., Hoff, Rani, Zaheer Hussain, Prause, N., Starcevic, V, Thorsten Quandt, Xavier Carbonell, Kardefelt-Winther, D, Carbonell, X, Dreier, Michael, Haagsma, MC, Pontes, Halley, Halley M. Pontes, Lopez Fernandez, Olatz, Maria C. Haagsma, Dreier, M., Kardefelt-Winther, Daniel, Kardefelt‐Winther, D., King, Daniel L., Mark Coulson, Michelle Carras, Müller, Kai, Haagsma, Maria C, van Rooij, Antonius J, Pallesen, S., van Rooij, Tony, Pontes, Halley M., Griffiths, Mark D., Griffiths, Mark D, van Rooij, Antonius J., Haagsma, Maria, Demetrovics, Zsolt, Hoff, RA, Pallesen, Ståle, Rani A. Hoff, Delfabbro, P., Van Rooij, AJ, Coulson, Mark, Hussain, Z., Kuss, DJ, Elias Aboujaoude, Katalin Nagygyorgy, Müller, K, Mark D. Griffiths, Carras, M, Prause, N, Derevensky, J, Aboujaoude, E., Demetrovics, Z., Carras, Michelle, Dreier, M, Hoff, Rani A., Quandt, T, King, D.L., Achab, S, Delfabbro, P, Achab, S., Christopher J. Ferguson, Ferguson, Christopher J., Quandt, T., Griffiths, M.D., Sophia Achab, Aboujaoude, Elias, Demetrovics, Z, Haagsma, M.C., King, DL, Hussain, Z, Zsolt Demetrovics, Jeffrey Derevensky, Coulson, M., Ferguson, Christopher, Ferguson, C.J., Pontes, HM, Müller, K., Hussain, Zaheer, Quandt, Thorsten   +126 more
core   +1 more source

A Novel Dual-Frequency Deep Brain Stimulation Paradigm for Parkinson’s Disease

Neurology and Therapy, 2019
Introduction Deep brain stimulation (DBS) of the subthalamic nucleus (STN) using high-frequency (130–185 Hz) stimulation (HFS) is more effective for appendicular than for axial symptoms.
Jessica A. Karl, Bichun Ouyang, Leo Verhagen Metman   +2 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source