Results 11 to 20 of about 2,284,468 (268)
Movement Disorders in Metabolic Disorders [PDF]
We provide a review of the movement disorders that complicate selected metabolic disorders, including the abnormal movements that may appear during or after their treatment.Movement disorders may be underrecognized when arising in the context of a broad range of metabolic disorders.
Pedroso, José Luiz +2 more
openaire +3 more sources
Intrinsically disordered proteins and their (disordered) proteomes in neurodegenerative disorders [PDF]
The recent years have witnessed a rise in the number of intrinsically disordered proteins (IDPs), also known as hybrid proteins, which possess both structured domains and biologically important intrinsically disordered protein regions (IDPRs). These proteins challenge the “one sequence—one structure—one function” concept by demonstrating that the lack ...
Vladimir N. Uversky +3 more
openaire +4 more sources
Mental disorders, brain disorders and values [PDF]
The debates about the normativity of mental disorders and about the distinction between somatic and mental disorders have long been closely linked. This is very obvious in Szasz, who claims that there can only be brain disorders, no mental disorders and that so-called mental disorders are really problems in living.
Anneli eJefferson, Anneli eJefferson
openaire +5 more sources
Personality Disorder Cognitions in the Eating Disorders [PDF]
Patients with eating disorder have relatively high rates of comorbid personality disorder diagnoses, including both anxiety-based personality disorders (obsessive-compulsive and avoidant) and borderline personality disorder. However, there is preliminary evidence that the core cognitions underlying personality pathology in the eating disorders are ...
Gabriel, C., Waller, G.
openaire +3 more sources
Mitochondrial disorders are among the most common heritable diseases, with an overall lifetime risk of approximately one in 1500. Nonetheless, their diagnosis is often missed because of their extreme phenotypic and genotypic heterogeneity.This review is based on publications retrieved by a selective literature search on the clinical features, genetics,
Klopstock, T. +5 more
openaire +4 more sources
Selective serotonin reuptake inhibitors in the treatment of generalized anxiety disorder [PDF]
Selective serotonin reuptake inhibitors have proven efficacy in the treatment of panic disorder, obsessive–compulsive disorder, post-traumatic stress disorder and social anxiety disorder.
Buis, C., Mayers, A.G., Baldwin, D.S.
core +1 more source
Inferring function using patterns of native disorder in proteins [PDF]
Natively unstructured regions are a common feature of eukaryotic proteomes. Between 30% and 60% of proteins are predicted to contain long stretches of disordered residues, and not only have many of these regions been confirmed experimentally, but they ...
Swindells, MB +14 more
core +1 more source
Mental disorders are not brain disorders [PDF]
AbstractAs advances in neuroscience and genetics reveal complex associations between brain structures, functions and symptoms of mental disorders, there have been calls for psychiatric classifications to be reconfigured, to conceptualize mental disorders as disorders of the brain.
openaire +3 more sources
Lamotrigine in the treatment of schizoaffective disorder [PDF]
There is accumulating evidence for the efficacy of lamotrigine in the treatment of bipolar disorder, including bipolar depression, both as monotherapy and in combination with sodium valproate.
Grunze, Heinz +2 more
core +1 more source
P-193 - Employment outcomes in people with bipolar disorder : a systematic review [PDF]
Objectives We conducted a systematic review in order to identify the long term employment outcomes of people with Bipolar Disorder. Our aims were to identify the proportions working over time, the nature of employment status change over time and whether
Marwaha, Steven +8 more
core +1 more source

