Results 31 to 40 of about 2,284,468 (268)

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

The use of clozapine in the treatment of bipolar disorder in a patient with clinical comorbidities [PDF]

, 2007
Introduction: Patients with bipolar disorder report impairments of social functioning and the maintenance of relationships. This compromise is often accompanied by executive functioning deficits across mood states and periods of euthymia.
Lagopoulos, Jim, Ceresér, Keila Maria Mendes, Cahill, C, Olley, A L, Brunstein, Miriam Garcia, Frey, B.N., Gonçalves, D.M., Kapczinski, Flávio Pereira, Santin, Aida Maria Pereira, Malhi, G S, Fernandes, B., Shnier, R C, Frey, Benício Noronha, Gomes, Fabiano Alves, Lobato, M.I.   +14 more
core   +1 more source

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker, Kyle Kemp, Perri Tutelman, Sharon H. J. Hou, Paul Fairie, Maria Santana, Gregory M. T. Guilcher, Taryn Fay‐McClymont, Glenda Bendiak, Wendy Pelletier, Nicola Wright, Fiona Schulte   +11 more
wiley   +1 more source

Putative Transcriptomic Biomarkers in the Inflammatory Cytokine Pathway Differentiate Major Depressive Disorder Patients from Control Subjects and Bipolar Disorder Patients [PDF]

, 2014
Mood disorders consist of two etiologically related, but distinctly treated illnesses, major depressive disorder (MDD) and bipolar disorder (BPD). These disorders share similarities in their clinical presentation, and thus show high rates of misdiagnosis.
Farmer, A., Farmer, Anne E, Powell, Timothy R, Matthews Keith, Day, Richard K, Anne E. Farmer (215007), Powell Timothy R., Farmer, Anne E., Hosang Georgina M., Farmer Anne E., Martin, C, Leonard C. Schalkwyk (27674), Day, Richard K., Cohen-Woods Sarah, Katherine E. Tansey (128003), Cohen-Woods, Sarah, Richard K Day, Timothy R. Powell (533562), McGuffin Peter, Day Richard K., Farmer, AE, Matthews, K, Hosang, GM, Schalkwyk, Leonard, Schalkwyk, L., Timothy R Powell, Keith Matthews (22202), Tansey, Katherine E., Powell, TR, Matthews, K., Tansey, Katherine E, Powell, Timothy; id_orcid, Georgina M Hosang, Sarah Cohen-Woods (214940), Tansey, K., Martin, Charlotte, Martin, C., Hosang, Georgina, McGuffin, P., Tansey Katherine E., D'Souza Ursula M., Matthews, Keith, Leonard C Schalkwyk, Schalkwyk Leonard C., Charlotte Martin (533565), Day, RK, Matthews, Kieth, Anne E Farmer, Martin Charlotte, Hosang, G., D'Souza, Ursula M., Charlotte Martin, Powell, T., McGuffin, P, Schalkwyk, LC, Peter McGuffin, Tansey, KE, Georgina M. Hosang (533564), Ursula M D'Souza, Sarah Cohen-Woods, Schalkwyk, Leonard C., D'Souza, U., D'Souza, Ursula M, Keith Matthews, Peter McGuffin (51507), Day, R., Hosang, Georgina M., Katherine E Tansey, McGuffin, Peter, Ursula M. D'Souza (533563), Cohen-Woods, S, McGuffin, Peter W, Schalkwyk, Leonard C, Cohen-Woods, S., Powell, Timothy R., D'Souza, UM, Richard K. Day (533566)   +76 more
core   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Predictors of employment in bipolar disorder : a systematic review [PDF]

, 2013
Background Severe work impairment can be present for a considerable proportion of the course of bipolar disorder (BD) and is costly for governments, services and individuals.
Marwaha, Steven, Eleanor Gilbert, Marwaha, Steven; id_orcid, Gilbert, Eleanor, Steven Marwaha   +4 more
core   +1 more source

Increased Risk of Sarcomas in Children With Congenital Anomalies: Findings From the Genetic Overlap Between Anomalies and Cancer in Kids (GOBACK) Registry Linkage Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters, Ji Yun Tark, Tiffany M. Chambers, Tania A. Desrosiers, Michael E. Scheurer, Charles Shumate, Wendy N. Nembhard, Mahsa M. Yazdy, Eirini Nestoridi, Amanda E. Janitz, Jean Paul Tanner, Russell S. Kirby, Jason L. Salemi, Yao Yu, Chad D. Huff, Sharon E. Plon, Philip J. Lupo, Jeremy M. Schraw   +17 more
wiley   +1 more source

Causes of attention deficit hyperactivity disorder [PDF]

, 2000
Plan BAs a society we often look at how we can fix current problems. This study takes another approach that has not been as well researched in the area of Attention Deficit Hyperactivity Disorder, and that is the potential causes of this highly diagnosed
Mertig, Daniel A.
core  

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

Risk taking behaviour in bipolar affective disorder [PDF]

, 2010
This piece of research was designed to explore the nature of risk taking behaviour and impulsivity in bipolar affective disorder. Involvement in pleasurable activities that have a high potential, or risk, for unwanted consequences forms one of the DSM IV
Bunch, Kristin
core