Results 41 to 50 of about 5,886,495 (367)

Cognitive behavior therapy in panic disorder and comorbid major depression - A naturalistic study [PDF]

, 2000
Background: There is a lack of evidence about the effectiveness of cognitive behavior therapies (CBT) in settings of routine clinical care as well as in the treatment of panic and comorbid disorders. Methods: We investigated a group-oriented CBT approach
Fichter, Manfred M., Trenkamp, Susanne, Rief, Winfried, Auer, Claudia   +3 more
core   +1 more source

Awaiting accurate scientific evidence: Progression or “profiles” in bipolar disorder?

International Journal of Bipolar Disorders, 2017
This letter is written in response to a review recently published in the journal. The aim is to highlight a potential methodological limitation common to many studies comparing bipolar patients with few previous episodes versus those with multiple ...
Diego J. Martino, Cecilia Samamé, Sergio A. Strejilevich   +2 more
doaj   +1 more source

Exon-phase symmetry and intrinsic structural disorder promote modular evolution in the human genome [PDF]

, 2013
A key signature of module exchange in the genome is phase symmetry of exons, suggestive of exon shuffling events that occurred without disrupting translation reading frame.
Kalmár, Lajos, Schád, Éva, Tompa, Péter   +2 more
core   +1 more source

Home-Based Titration with Duodenal Infusion of Levodopa-Carbidopa Intestinal Gel in People with Parkinson’s Disease: An Observational Feasibility Study

Parkinson's Disease
Background. Testing and titration of the right levodopa equivalent dose are usually performed during a hospital admission. However, optimal dose titration in people with Parkinson’s disease (PwPs) may depend on home environment, emotional stress, and ...
Trine Hørmann Thomsen, Nick Schou Nielsen, Asher Lou Isenberg, Michael Hougaard Møller, Jesper Bøje Clausen, Inge Mona Schack Frederiksen, Louise Olsen, Mahsa Javidi, Jeanet Vilhelmsen, Marc Klee Olsen, Bo Biering-Sørensen   +10 more
doaj   +1 more source

Secondary outcomes and qualitative findings of an open-label feasibility trial of lisdexamfetamine dimesylate for adults with bulimia nervosa

Journal of Eating Disorders, 2023
Background There is emerging evidence that stimulants warrant further investigation as a treatment for bulimia nervosa (BN) including a recent open-label feasibility trial examining the use of lisdexamfetamine dimestylate (LDX) for BN. The current report
Laura Dixon, Sara Bartel, Victoria Brown, Sarrah I. Ali, Susan Gamberg, Andrea Murphy, Katherine L. Brewer, Susan L. McElroy, Allan Kaplan, Abraham Nunes, Aaron R. Keshen   +10 more
doaj   +1 more source

Genomic Diversity and Clinical Variability in Pediatric Primary Cutaneous Anaplastic Large Cell Lymphoma: A Case Series

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare pediatric CD30‐positive T‐cell lymphoproliferative disorder with an excellent prognosis, but its genomic drivers are poorly defined. We report three children with skin‐limited disease demonstrating striking molecular heterogeneity, including NPM::ALK, NUP214::FRK, and a novel ...
Shoshana Greenberger, Efrat Bar‐Ilan, Victoria Marcu, Evgeny Grishin, Rinat Yacobi, Aviv Barzilai, Hana Golan, Assaf Arie Barg   +7 more
wiley   +1 more source

Epidemiology of DSM-5 Alcohol Use Disorder

JAMA psychiatry, 2015
IMPORTANCE National epidemiologic information from recently collected data on the new DSM-5 classification of alcohol use disorder (AUD) using a reliable, valid, and uniform data source is needed.
Bridget F. Grant, R. Goldstein, T. Saha, S. Chou, Jeesun Jung, Haitao Zhang, R. Pickering, W. J. Ruan, Sharon M. Smith, Boji Huang, D. Hasin   +10 more
semanticscholar   +1 more source

Attention-deficit/hyperactivity disorder: a closer look [PDF]

, 1999
Plan BThis paper examines Attention-Deficit Hyperactivity Disorder. More specifically, the aim of this paper is to discuss some of the many operational definitions of ADHD.
O'Neill, Michael J.
core   +1 more source

Genome-wide association study of major depressive disorder: new results, meta-analysis, and lessons learned [PDF]

, 2010
Major depressive disorder (MDD) is a common complex disorder with a partly genetic etiology. We conducted a genome-wide association study of the MDD2000+ sample (2431 cases, 3673 screened controls and >1 M imputed single-nucleotide polymorphisms (SNPs)).
D I Boomsma, Maclean, A. W., Sullivan, P.F., Sullivan, P F, G Willemsen, de Geus, E.J.C., D J Statham, Willemsen, G.; id_orcid, Gordon, SD, Penninx, BWJH, Smit, J H, Medland, S E, Maclean, A.W., S E Medland, Penninx, B. W. J. H., van den Oord, E J C G, Montgomery, G W, Pergadia, M L, Byrne, E.M., Heath, A.C., Martin, N.G., MacIntyre, Donald; id_orcid, Hickie, I.B., Statham, D.J., C M Middeldorp, E M Byrne, B W J H Penninx, Nyholt, D.R., J J Hottenga, J H Smit, A K Henders, Blackwood, D.H., Liu, J. Z., N G Martin, A W Maclean, Lewis, C.M., Montgomery, G. W., McGuffin, P, S D Gordon, McEvoy, B.P., MacIntyre, D J, McGhee, K A, P A F Madden, MacIntyre, D J; id_orcid, Pergadia, M. L., van den Oord, E.J., McEvoy, B P, Gordon, S.D., Martin, N. G., D H R Blackwood, P F Sullivan, De Geus, E. J. C., Montgomery, G.W., Hottenga, J.J., Hickie, I. B., McGhee, K.A., Medland, S. E., C M Lewis, J Z Liu, Gordon, S D, Smit, J. H., Boomsma, D. I., Hottenga, J. J., Smit, J.H., Middeldorp, C.M., Ripke, S., M L Pergadia, Hickie, I B, de Geus, E.J., Wray, NR, Van Den Oord, E. J. C. G., Wray, N. R., Blackwood, DHR, de Geus, E J C, Penninx, B.W., B P McEvoy, McGhee, K. A., Middeldorp, C. M., Byrne, E. M., McEvoy, B. P., Macgregor, S, E J C G van den Oord, Statham, D J, Heath, A C, Lewis, C. M., van den Oord, E.J.C.G., I B Hickie, Willemsen, G., Pergadia, M.L., Medland, S.E., Sullivan, P. F., Penninx, B.W.J.H., Heath, A. C., Maclean, AW, Nyholt, D. R., N R Wray, S Macgregor, MacIntyre, DJ, Boomsma, D.I., G W Montgomery, Lewis, C M, Henders, A K, Madden, P. A. F., Madden, P.A.F., Henders, A.K., Hottenga, J J, McGuffin, P., Boomsma, D I, Madden, P.A., de Geus, E.J.C.; id_orcid, Oord, E.J.C.G. van den, Henders, A. K., Wray, N R, Madden, P A F, E J C de Geus, Pergadia, ML, D R Nyholt, Maclean, A W, Ripke, S, A C Heath, Ripke, Stephan, MacIntyre, D. J., Geus, E.J.C. de, Blackwood, D. H. R., Statham, D. J., Penninx, B W J H, Macgregor, S., Gordon, S. D., McGhee, KA, D J MacIntyre, Nyholt, D R, Wray, N.R., Middeldorp, C M, Liu, J Z, S Ripke, K A McGhee, P McGuffin, Nyholt, DR, Willemsen, G, Boomsma, D.I.; id_orcid, Lewis, C. M.; id_orcid, Martin, N G, Blackwood, D H R, Liu, J.Z., Byrne, E M, MacIntyre, D.J.   +145 more
core   +1 more source

Lessons from the National institutes of health innovation corps program: defining barriers to developing and commercializing novel solutions for persons with opioid use disorder

Addiction Science & Clinical Practice
Background Translating innovative research advancements into commercially viable medical interventions presents well-known challenges. However, there is limited understanding of how specific patient, clinical, social, and legal complexities have further ...
Matthew P. Heshmatipour, Tyler M. Duvernay, Desislava Z. Hite, Eboo Versi, Michael P. Hite, David F. Reeser, Victor Prikhodko, Ariana M. Nelson, Bina Julian, Milton L. Greenberg   +9 more
doaj   +1 more source