Results 41 to 50 of about 152,466 (362)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Genetics and Molecular Biology, 2002 Hydromedusa maximiliani is a vulnerable neotropical freshwater turtle endemic to mountainous regions of the Atlantic rainforest in southeastern Brazil.
Franco L. Souza +4 more
doaj +1 more source
International Statistical Review / Revue Internationale de Statistique, 1987 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Speed, T. P., Bailey, R. A.
openaire +2 more sources
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Ecology and Evolution, 2021 The natural and seminatural components of agricultural landscapes play a key role in maintaining a high level of biodiversity. Being the Po Valley one of the most human‐dominated and intensively cultivated landscapes in Europe, we investigated the effect
Francesca Della Rocca +3 more
doaj +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Rapid evolution of dispersal ability makes biological invasions faster and more variable
Nature Communications, 2017 Genetic variation in dispersal ability may result in the spatial sorting of alleles during range expansion. Recent theory suggests that spatial sorting can favour the rapid evolution of life history traits at expanding fronts, and therefore modify the ...
Brad M. Ochocki, T. Miller
semanticscholar +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Some recent developments on linear determinacy
Mathematical Biosciences and Engineering, 2013 The process of invasion is fundamental to the study of the dynamics of ecological and epidemiological systems. Quantitatively, a crucial measure of species' invasiveness is given by the rate at which it spreads into new open environments.
Carlos Castillo-Chavez +2 more
doaj +1 more source
Conservation Letters, 2022 Fire can promote biodiversity, but changing patterns of fire threaten species worldwide. While scientific literature often describes ‘‘inappropriate fire regimes’’ as a significant threat to biodiversity, less attention has been paid to the ...
Julianna L. Santos +6 more
doaj +1 more source