Results 81 to 90 of about 948,438 (322)
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Study the Dispersion and Losses in Fiber Optics Communication [PDF]
, 2023 S. V. Kumari, Achint Raj -
openalex +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Dispersive Sweatt Model for Broadband Lens Design with Metasurfaces
PhotonicsThe Sweatt model has been extensively used to design optical systems containing diffractive optical elements (DOEs) because it captures the dispersive characteristics of DOEs.
Weiyu Chen, Ko-Han Shih, C. Kyle Renshaw
doaj +1 more source
Cascaded forward Brillouin scattering to all Stokes orders
New Journal of Physics, 2017 Inelastic scattering processes such as Brillouin scattering can often function in cascaded regimes and this is likely to occur in certain integrated opto-acoustic devices.
C Wolff +4 more
doaj +1 more source
Alexandria Engineering Journal, 2020 A cost efficient and reliable single mode fiber and free space optics based hybrid 32×5Gbps ultra dense wavelength division multiplexed-passive optical network architecture employing optical comb and polarization multiplexing is proposed.
Jawad Mirza +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Cholesteric Liquid Crystal Materials for Tunable Diffractive Optics
Advanced Optical Materials, 2018 Modern optics and photonics constantly require break‐through materials and designs in order to achieve miniature, lightweight, highly tunable, and effective optical devices. One of the basic optical components is the diffraction grating (DG), widely used
A. Ryabchun, A. Bobrovsky
semanticscholar +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source