Results 61 to 70 of about 83,539 (316)

Investigating the molecular dissolution process of binary solid dispersions by molecular dynamics simulations

Asian Journal of Pharmaceutical Sciences, 2018
Dissolution molecular mechanism of solid dispersions still remains unclear despite thousands of reports about this technique. The aim of current research was to investigate the molecular dissolution mechanism of solid dispersions by molecular dynamics ...
TengIan Chan, Defang Ouyang
doaj   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke, Christian Thomas, Michael C. Frühwald, Pascal D. Johann, Martin Hasselblatt   +4 more
wiley   +1 more source

Structure of amphiphilic block copolymer micelles in aqueous dispersions [PDF]

, 2003
Two molecular weight series of Poly(butadiene)-Poly(ethylene oxide) diblock copolymers have been synthesised using anionic polymerisation techniques.
Leslie, Stuart
core  

Preparation and characterisation of solid dispersions of tanshinone IIA, cryptotanshinone and total tanshinones

Asian Journal of Pharmaceutical Sciences, 2017
Total tanshinones are lipophilic active constituents extracted from Salvia miltiorrhiza Bge. Tanshinone IIA and cryptotanshinone are the major components in total tanshinones.
Xifeng Zhai, Chunguang Li, George Binh Lenon, Charlie C.L. Xue, Weize Li   +4 more
doaj   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source

Enhancing Dissolution of Ibuprofen via Solid Dispersion Using Hydrophilic Carrier and Fast Dissolving Sugars

Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2014
In this study, solid dispersion using hydrophilic carriers (polyethylene glycols) and fast dissolving sugars (sorbitol and lactose) has been employed to enhance dissolution and hence the bioavailability of ibuprofen.
Wedad Kamal Ali, Methaq Hamad Sabar, Athmar Dhahir Habeeb, Zainb Hassan Mahdi   +3 more
doaj   +1 more source

Enhancement of dissolution of atorvastatin through preparation of polymeric solid dispersions using supercritical fluid technology

Research in Pharmaceutical Sciences, 2020
Background and purpose: This study aimed at preparation of solid dispersions in order to enhance dissolution of poorly water-soluble atorvastatin using supercritical CO2 technology.
Bashar Altaani, Rana Obaidat, Walaa Malkawi   +2 more
doaj   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási, Bernadett Borbála Huszti, Gábor Barna, Marko Kavcic, Janez Jazbec, Lennart Lenk, Vera Münch, Sophia Polychronopoulou, Ágnes Márk, Maria Thastrup, Lüder H. Meyer, Kjeld Schmiegelow, Cornelia Eckert, Christina Halsey, Dániel J. Erdélyi   +14 more
wiley   +1 more source

Ion-Exchange Synthesis of Molybdenum Blue Dispersions: Colloidal Properties, Self-Assembly and Thermal Phase Transformation

Colloids and Interfaces
High-purity precursors are often required for the targeted synthesis of functional nanomaterials. Molybdenum blue (MB) dispersions are promising precursors for the production of functional materials based on molybdenum oxides and carbides. Here, a facile,
Dmitry Chertin, Natalia Gavrilova, Ilya Zavidovskiy, Maria Myachina, Alexander Syuy, Victor Nazarov   +5 more
doaj   +1 more source

Application of micro- and nano-bubbles in spray drying of milk protein concentrates

Journal of Dairy Science, 2022
: Micro- and nano-bubbles (MNB) have unique properties and have attracted great attention in the past 2 decades, offering prospective applications in various disciplines.
K.S. Babu, J.K. Amamcharla
doaj   +1 more source