Results 1 to 10 of about 50,651 (209)
Characterization of recrystallized itraconazole prepared by cooling and anti-solvent crystallization
The objective of the present study was to alter the crystal habit of itraconazole (ITZ) by cooling and anti-solvent crystallization and characterize its properties.
Pornsak Sriamornsak +1 more
doaj +1 more source
ENHANCED DISSOLUTION RATE OF IBUPROFEN USING SURFACTANTS AND WATER SOLUBLE CARRIERS [PDF]
The influence of some non-ionic surfactants as well as polyethylene glycol 6000 and dextrose as water soluble carrier, on the dissolution of poorly soluble drug, ibuprofen, was studied.
A. Abd El-Gawad, A. Nouh, M. El-Shaboury
doaj +1 more source
Solid dispersion (SD) is the effective approach to improve the dissolution rate and bioavailability of class II drugs with low water solubility and high tissue permeability in the Biopharmaceutics Classification System.
Qingyun Zeng +6 more
doaj +1 more source
The crystal changes and salt formation of poorly water-soluble telmisartan (TEL) in various solvents were investigated for enhanced solubility, stability and crystallinity. Polymorphic behaviors of TEL were characterized by dispersing in distilled water,
Chulhun Park +9 more
doaj +1 more source
While spray-drying has been widely utilized to improve the bioavailability of poorly water-soluble drugs, the outcomes often exhibit suboptimal particle size distribution and large particle sizes, limiting their effectiveness. In this study, we introduce
Jung Suk Kim +12 more
doaj +1 more source
Efficient Drug Loading Method for Poorly Water-Soluble Drug into Bicelles through Passive Diffusion. [PDF]
Arai Y +4 more
europepmc +1 more source
The formulation development for poorly soluble drugs still remains a challenge. Supersaturating drug delivery systems (SDDS) or drug delivery systems based on supersaturating provide a promising way to improve the oral bioavailability of poorly water ...
Meiyan Yang +5 more
doaj +1 more source
Solubility Enhancement of a Poorly Water-Soluble Drug Using Hydrotropy and Mixed Hydrotropy-Based Solid Dispersion Techniques. [PDF]
Abdullah Ali H, Kamal Omer H.
europepmc +1 more source
Mechanistic study of the solubilization effect of basic amino acids on a poorly water-soluble drug. [PDF]
Alsalhi MS, Royall PG, Chan KLA.
europepmc +1 more source
We applied a combination of inorganic mesoporous silica material, frequently used as drug carriers, and a natural organic polymer alginate (ALG), to establish a sustained drug delivery system for the poorly water-soluble drug Indomethacin (IND ...
Liang Hu +7 more
doaj +1 more source

