Results 11 to 20 of about 7,969,000 (286)
Solubilization and Controlled Release Strategy of Poorly Water-Soluble Drugs
Pharmaceuticals, 2022 The processes of solubilization and controlled release of drugs that are poorly soluble in water are highly relevant in drug preformulation studies in pharmaceutical development [...]
M. A. Peña
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Hydrogel-Based Drug Delivery Systems for Poorly Water-Soluble Drugs [PDF]
Molecules, 2015 Hydrogels are three-dimensional materials that can withstand a great amount of water incorporation while maintaining integrity. This allows hydrogels to be very unique biomedical materials, especially for drug delivery.
Matthew McKenzie +5 more
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International Journal of Nanomedicine, 2012 Zhouhua Wang,1,2 Bao Chen,1 Guilan Quan,1 Feng Li,1 Qiaoli Wu,1 Linghui Dian,1 Yixuan Dong,1 Ge Li,2 Chuanbin Wu1,21School of Pharmaceutical Sciences, 2Research and Development Center of Pharmaceutical Engineering, Sun Yat-sen University, Guangzhou ...
Li G +8 more
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Drug delivery strategies for poorly water-soluble drugs [PDF]
Expert Opinion on Drug Delivery, 2007 The drug candidates coming from combinatorial chemistry research and/or the drugs selected from biologically based high-throughput screening are quite often very lipophilic, as these drug candidates exert their pharmacological action at or in biological membranes or membrane-associated proteins. This challenges drug delivery institutions in industry or
Alfred, Fahr, Xiangli, Liu
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Recent Technologies for Amorphization of Poorly Water-Soluble Drugs [PDF]
Pharmaceutics, 2021 Amorphization technology has been the subject of continuous attention in the pharmaceutical industry, as a means to enhance the solubility of poorly water-soluble drugs. Being in a high energy state, amorphous formulations generally display significantly increased apparent solubility as compared to their crystalline counterparts, which may allow them ...
Dohyun Kim +6 more
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Lipid-based oral formulation in capsules to improve the delivery of poorly water-soluble drugs
Frontiers in Drug Delivery, 2023 Poorly water-soluble drugs demonstrate significant challenge in pharmaceutical development, which is linked to their limited oral bioavailability and therapeutic efficacy.
Popat Mohite +4 more
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Drug Delivery Strategies for Poorly Water-Soluble Drugs
, 2013 Many newly proposed drugs suffer from poor water solubility, thus presenting major hurdles in the design of suitable formulations for administration to patients.
Douroumis, Dionysios
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Pharmaceuticals, 2022 This study aimed to construct a pH-responsive nanocrystalline hydrogel drug delivery system for topical delivery of insoluble drugs based on the self-assembly behavior of carboxymethyl chitosan (CMC) and oxidized hyaluronic acid (OHA).
Xiaohan Tang +3 more
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Phytomedicine Plus, 2021 Background: Poorly water-soluble medicaments continue to be a challenging, however, significant class of herbal drugs for the management of an extensive range of ailments.
Shahid Ud Din Wani +6 more
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Asian Journal of Pharmaceutical Sciences, 2016 A simple method to fabricate itraconazole (ITZ)-loaded pectin nanoparticles prepared from nanoemulsion templates is described in this study. Nanoemulsions containing ITZ were prepared by a mechanical homogenization using pectin as emulsifier.
Kanokporn Burapapadh +2 more
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