Results 141 to 150 of about 2,944,881 (380)

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

open access: yesMolecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche   +8 more
wiley   +1 more source

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

open access: yesMolecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides   +13 more
wiley   +1 more source

State practice and the family unity of African refugees [PDF]

open access: yesForced Migration Review, 2007
As African and Northern states increasingly prioritise immigration control and economic and security considerations, families are being pulled apart. In the UK detention and deportation prevent reunification and actively disrupt family unity.
Esther Sample
doaj  

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

open access: yesMolecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh   +5 more
wiley   +1 more source

Computational modelling of cracks in viscoplastic media [PDF]

open access: yes, 2001
A newly developed numerical model is used to simulate propagating cracks in a strain softening viscoplastic medium. The model allows the simulation of displacement discontinuities independently of a finite element mesh.
De Borst, R, Sluys, LJ, Wells, GN
core  

Displacement [PDF]

open access: yesPERIPHERIE – Politik • Ökonomie • Kultur, 2015
Schultz, Ulrike, Zwick, Maja
openaire   +2 more sources

Decrypting cancer's spatial code: from single cells to tissue niches

open access: yesMolecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik   +4 more
wiley   +1 more source

Thickness variation parameter in a thin rotating disc by finite deformation [PDF]

open access: yesFME Transactions, 2013
Seth’s transition theory is applied to the problems of thickness variation parameter in a thin rotating disc by finite deformation. Neither the yield criterion nor the associated flow rule is assumed here.
Pankaj Thakur, Singh S.B., Jatinder Kaur
doaj  

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