Results 61 to 70 of about 2,289,456 (329)
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Forced Migration Review, 2017 States in the Americas confront complex challenges in the face of human mobility caused by both sudden- and slow-onset disasters. A new regional guide presents practices and measures to help address the protection needs of cross-border disaster-displaced
Walter Kälin, David Cantor
doaj
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
SSM - Mental HealthImmigrant agricultural workers, especially unauthorized workers, face a range of severe stressors, including isolation, chronic job insecurity, and marginalization, leading to higher rates of mental health issues compared to native-born populations. This
Helen Elizabeth Lindsay +2 more
doaj +1 more source
, 2017 Despite the large improvements in performance attained by using deep learning in computer vision, one can often further improve results with some additional post-processing that exploits the geometric nature of the underlying task. This commonly involves
Kokkinos, Iasonas, Neverova, Natalia
core
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Lensing by Kerr Black Holes. II: Analytical Study of Quasi-Equatorial Lensing Observables
, 2011 In this second paper, we develop an analytical theory of quasi-equatorial lensing by Kerr black holes. In this setting we solve perturbatively our general lens equation with displacement given in Paper I, going beyond weak-deflection Kerr lensing to ...
A. O. Petters +8 more
core +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Towards a development approach to displacement
Forced Migration Review, 2017 To better respond to displacement, we need to adopt a medium- to long-term perspective rooted in development as well as humanitarian principles.
Xavier Devictor
doaj
Displacement of Histones at Promoters of \u3ci\u3eSaccharomyces cerevisiae\u3c/i\u3e Heat Shock Genes Is Differentially Associated with Histone H3 Acetylation [PDF]
, 2006 Chromatin remodeling at promoters of activated genes spans from mild histone modifications to outright displacement of nucleosomes in trans. Factors affecting these events are not always clear.
Erkina, Tamara Y., Erkine, Alexander M.
core +1 more source