Results 111 to 120 of about 242,073 (299)

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

A Study of Member Displacement According to Seasonal Climate of the Sungnyemun Gate, a Korean Wooden Architectural Heritage Site

open access: yesBuildings
This study analyzes the results of a displacement measurement of the Sungnyemun Gate’s structural members, such as column, girder, and hip rafter, carried out by the National Institute of Cultural Heritage for about 10 years from December 2013 to October
Hyowon Seo, Hana Lee, Sunghan Kim
doaj   +1 more source

Innovation by Displacement

open access: yes
40 papges, 15 ...
Linzhuo Li, Yiling Lin, Lingfei Wu 0002
openaire   +2 more sources

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Investigation of Hatay-Defne earthquake (20.02.2023) by using GNSS station

open access: yesGeodesy and Cartography
No studies have been conducted on the spatial changes related to the Hatay-Defne earthquake (20 February 2023) up to now. The reason for this situation is that the requested data cannot be accessed as a result of the power and internet interruptions ...
Atınç Pırtı   +2 more
doaj   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Calculation models of beams with one-way connections

open access: yesВестник Дагестанского государственного технического университета: Технические науки
Objective. The article considers the operational features of beam structures with one-way ties. Method. By studying the operational features of beam structure supports, analytical and graphical dependencies between beam displacements and their support ...
A. K. Yusupov   +2 more
doaj   +1 more source

Ranking femoral head displacements.

open access: yes, 2018
Femoral head displacements in millimeters [mm] during peak HCFs ranked from right to left for the highest (blue) to the lowest displacement (red).
Pim Pellikaan (5059523)   +4 more
core   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

open access: yesFEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

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