Drug-induced agranulocytosis: a disproportionality analysis and umbrella review [PDF]
Frontiers in PharmacologyBackgroundDrug-induced agranulocytosis (DIA) is a rare but life-threatening hematologic disorder that demands increased clinical and research attention. This study aimed to provide the current overview of DIA for clinical guidance.MethodsUsing real-world
Yajie Lu +11 more
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Anti-NMDA receptor encephalitis and vaccination: A disproportionality analysis
Frontiers in Pharmacology, 2022 Anti–N-methyl-D-aspartate receptor (NMDAR) encephalitis is an auto-immune neurological disorder characterized by the presence in the cerebrospinal fluid (CSF) of antibodies against the GluN1 subunit of NMDA receptors in the brain.
Salomé Martin +3 more
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Contributions of Pharmacovigilance to the Understanding of Risks Associated with Ibuprofen: Descriptive and Disproportionality Analysis Using FAERS Data [PDF]
PharmaceuticalsBackground/Objectives: The objective of this study was to evaluate real-world evidence (Food & Drug Administration database, FAERS) on ibuprofen adverse events (AE) through descriptive and disproportionality analyses.
Cristina Anamaria Buciuman +12 more
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Disproportionality analysis of biliary adverse events associated with fibrates using the JADER and FAERS databases [PDF]
Frontiers in PharmacologyIntroductionFibrates are effective triglyceride-lowering drugs, but they may affect bile acid metabolism, raising concerns about biliary adverse drug events (ADEs).ObjectiveIn this study, we used spontaneous reporting system databases to evaluate the ...
Satoko Watanabe +6 more
doaj +2 more sources
Adverse events associated with statin co-use in breast cancer patients: a disproportionality analysis based on the FDA Adverse Event Reporting System [PDF]
Therapeutic Advances in Drug SafetyBackground: An increasing number of breast cancer patients are using statins concomitantly. However, there are relatively few safety studies on the association between statins and adverse events (AEs) during breast cancer treatment. Objective: This study
Yunnan Zhang +5 more
doaj +2 more sources
Risk of pulmonary fungal infections associated with biologics: a FAERS database disproportionality analysis [PDF]
Frontiers in ImmunologyObjectivebiologics have significantly advanced the treatment of rheumatoid arthritis (RA) and psoriatic arthritis (PsA). However, real-world data regarding the risks of pulmonary fungal infections (PFI) associated with different biologics are limited ...
Jing Li +4 more
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Charting and Sidestepping the Pitfalls of Disproportionality Analysis. [PDF]
Drug SafDisproportionality analysis is used by many pharmacovigilance organizations for detecting and assessing signals of potential adverse drug reactions. However, its goal is often misunderstood and the approach misapplied, leading to erroneous conclusions due to neglected violated assumptions.
Fusaroli M +3 more
europepmc +3 more sources
Finite element analysis of disproportionate regions [PDF]
Proceedings of the Second International Symposium of Trans Black Sea Region on Applied Electromagnetism (Cat. No.00TH8519), 2002 Summary form only given. The paper deals with the problem of the electromagnetic field analysis in incommensurable regions. These are cases when there is a need for detailed field calculation in a small region, which is a part of larger one.
R. Stancheva, I. Latcheva
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Thermodynamic analysis on disproportionation process of cyclohexylamine to dicyclohexylamine [PDF]
Polish Journal of Chemical Technology, 2021 Abstract This work deals with a study of the effect of temperature on the cyclohexylamine disproportionation to dicyclohexylamine, conjointly with the thermodynamic analysis of this process. The laboratory experiments were carried out in a glass tubular continuous-flow reactor in a gaseous phase at the reaction ...
Roman Valeš +2 more
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Risk of bronchospasm and coronary arteriospasm with sugammadex use: a post marketing analysis
Therapeutic Advances in Drug Safety, 2019 Introduction: Sugammadex is used for the reversal of neuromuscular blockade caused by rocuronium bromide and vecuronium bromide. As part of the post licensing phase of drug development, adverse events related to the use of sugammadex are still being ...
Pushkar Aggarwal
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