Results 71 to 80 of about 6,509 (259)

Comparison of safety of lecanemab and donanemab: a real-world disproportionality analysis using the FDA adverse event reporting system

Frontiers in Pharmacology
BackgroundLecanemab and donanemab are anti-amyloid-β (Aβ) monoclonal antibodies recently approved for the treatment of Alzheimer’s disease (AD). Although both agents have demonstrated therapeutic potential, their post-marketing adverse event reporting ...
Xiuping Feng, Xiuping Feng, Shangqing Bi, Shangqing Bi, Chaoqiong Shi, Chaoqiong Shi, Qingqing Chang, Qingqing Chang, Jiaming Zhang, Jiaming Zhang, Yiyang Zhuang, Yiyang Zhuang   +11 more
doaj   +1 more source

Maternal and Neonatal Complications Associated with Breast Cancer Systemic Treatments—A VigiBase Disproportionality Analysis Study

Clinical Pharmacology &Therapeutics, EarlyView.
Pregnancy‐associated breast cancer (PrBC) presents therapeutic challenges. Understanding maternal–fetal safety of systemic anticancer therapies is critical. We performed a case/non‐case disproportionality analysis using the WHO global pharmacovigilance database up to January 2024, to evaluate maternal–fetal outcomes associated with breast cancer (BC ...
Rayan Kabirian, Floriane Jochum, Elise Dumas, Florence Coussy, Kevin Bihan, Bénédicte Lebrun‐Vignes, Barbara Pistilli, Marc‐Antoine Benderra, Lise Selleret, Laurent Chouchana, Fabien Reyal, Anne‐Sophie Hamy, Paul Gougis   +12 more
wiley   +1 more source

Does ESG Uncertainty Matter for Renewable and Nonrenewable Energy Consumption? Policy Implications in the Context of SDG 7 and SDG 13

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT In the discourse on environmental sustainability and energy security, energy management is an inevitable policy issue that requires research‐based solutions. Based on this, the present study contributes by examining the impact of environmental, social, and governance (ESG) uncertainty on energy consumption patterns in the USA from 2002 to 2024.
Naif Alsagr, Qasim Raza Syed, Ahsan Anwar   +2 more
wiley   +1 more source

Signal detection of adverse events in medical devices using natural language processing: a case study in pelvic mesh

Scientific Reports
Disproportionality analysis is used to detect safety signals for post-market surveillance from adverse events reported to regulatory bodies but is challenging when reports contain unstructured free-text. We implemented a proof-of-concept system combining
Thu-Lan Kelly, Ty Stanford, Curtis Murray, Lewis Mitchell, Indu Bala, Nicole Pratt, Tobin South, Renly Lim, Marianne Gillam   +8 more
doaj   +1 more source

Peer Review in Pharmacovigilance: Lens on Disproportionality Analysis

Drug Safety
No abstract ...
Raschi E., Salvo F., Bate A., De Ponti F., Poluzzi E., Tuccori M., van Puijenbroek E., Joshi N., Khouri C.   +8 more
openaire   +5 more sources

Strategic Integration or Compliance Lag? Mapping Trends and Evolution of SBSC Through the Lens of the ESRS Framework

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT The sustainability balanced scorecard (SBSC) has become an influential framework for integrating sustainability into strategic management. Despite its growing adoption, research remains fragmented, and insufficiently aligned with the sustainability regulatory frameworks.
Biagio Maria Amico, Rafaela Gjergji, Valentina Lazzarotti   +2 more
wiley   +1 more source

Nanocubes and Cuboctahedra: Entropic Stabilization Versus Thermal Segregation in Rock Salt‐ and Spinel‐Type Multinary Oxides from Spray‐Flame Synthesis

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Spray‐flame synthesis enables highly flexible and scalable production of multinary and high‐entropy oxide nanoparticles due to high synthesis temperatures with subsequent quenching. Temperature‐dependent in situ diffraction of as‐synthesized materials clearly reveals entropy stabilization in rock salt lattices, while spinels—featuring tetrahedral and ...
Mohammed‐Ali Sheikh, Steven Angel, Sabrina Schleich, Leon Müller, Jan Ternieden, Hatem M. A. Amin, Christof Schulz, Hartmut Wiggers   +7 more
wiley   +1 more source

How to report neurotechnology and artificial intelligence studies in epilepsy: Peer‐review‐inspired recommendations

Epilepsia Open, EarlyView.
Abstract Objective The integration of neurotechnology and artificial intelligence (AI) in epilepsy research has led to significant advancements in diagnosis, monitoring, and treatment. However, the impact of these innovations is often diminished by inadequate and inaccurate reporting, limiting their reproducibility and implementation.
Pedro F. Viana, Matthew McWilliam, Andrea Biondi, Jesus Servando Medel‐Matus, Naoto Kuroda, Giulia Sofia Cereda, Aristea S. Galanopoulou   +6 more
wiley   +1 more source

Therapeutic Ineffectiveness of Calcitonin Gene-Related Peptide Antagonists: A Real-World Pharmacovigilance Analysis

Cyprus Journal of Medical Sciences
BACKGROUND/AIMS: Migraine is treated with a variety of drugs with different pharmacological mechanisms of action. Among these drugs, calcitonin gene-related peptide (CGRP) antagonists represent a novel approach to the treatment of migraine.
Nesrin Çağlayan Duman
doaj   +1 more source

External Validation of Pre‐Treatment Primary Tumor Volume as a Prognostic Factor in Head and Neck Cancer Treated With (Chemo)Radiotherapy

Head &Neck, EarlyView.
ABSTRACT Background Primary tumor volume (GTVp) is a key prognostic factor in oropharyngeal squamous cell carcinoma (OPSCC) treated with radiotherapy. We aimed to externally validate this association and assess its relevance in other head and neck sites.
Gabriel Adrian, Andre Haraldsson Änghede, Lachlan McDowell, Maria Gebre‐Medhin   +3 more
wiley   +1 more source