Results 81 to 90 of about 23,074,058 (199)

Disproportionality analysis of European safety reports on autoimmune and rheumatic diseases following COVID-19 vaccination

Scientific Reports
The safety profile of COVID-19 vaccines is well-established, yet the widespread immunization campaign has led to an increase in reported cases of Immune-Mediated and Rheumatic Diseases (IMDRs).
Federica Fraenza, Cecilia Cagnotta, Mario Gaio, Liberata Sportiello, Cristina Scavone, Annalisa Capuano, Ugo Trama   +6 more
doaj   +1 more source

Drugs Associated with Pediatric Cataracts: A Real-World Pharmacovigilance Study

Children
Background: Pediatric cataracts are a main cause of irreversible vision loss and a significant public health challenge. This study aimed to identify pharmacovigilance signals by analyzing large-scale data from the U.S.
Jiantong Du, Chen Xing, Zhiyue Zhang, Zonghui Ma   +3 more
doaj   +1 more source

Drug-induced hearing disorders: a disproportionality analysis of the FAERS database

Frontiers in Pharmacology
BackgroundTo evaluate and identify reports of adverse events related to hearing impairment with drugs approved in the past 20 years, to identify new adverse reaction signals related to hearing impairment that have not yet been reported, and to improve the safety of drug treatments.MethodsThe adverse event report data from the FAERS database from the ...
Baojian Li, Xiaoling Hu, Zichen Yue
openaire   +3 more sources

Age-stratified safety signal mining of ADHD medications in pediatric populations using the FAERS database (2014–2024): a pharmacovigilance study using multi-method disproportionality analysis

Frontiers in Pediatrics
BackgroundPediatric attention-deficit/hyperactivity disorder (ADHD) medications have been analyzed in the FDA Adverse Event Reporting System (FAERS), yet systematic age-stratified signal profiling under ICH E11(R1) developmental categories, covering the ...
Guangping Qin, Ling Chen
doaj   +1 more source

Disproportionality analysis of drug-induced dry mouth using data from the United States food and drug administration adverse event reporting system database

Heliyon
Background: Drug-induced dry mouth is an adverse reaction that can significantly affect the quality of life and mental state of patients. In this study, we aimed to identify the most common drugs associated with dry mouth using data from the United ...
Dan Xu, Hong Zhu, Meng Wu
doaj   +1 more source

Secondary data analysis of disproportionality and disparity in child welfare

, 2010
This project began by examining the historical roots of Black/African American culture in relation to the development of child welfare. This project was a secondary analysis of qualitative and quantitative data from research at the federal (macro), state
Dean T. Jones
core  

Androgenetic alopecia drugs and male infertility: Evidence from pharmacovigilance and testicular transcriptomics.

PLoS ONE
ObjectiveTo identify disproportionality signals linking androgenetic alopecia (AGA) drugs (finasteride, dutasteride, and minoxidil) with male infertility-related adverse events and to explore infertility-related biological features using testicular ...
Zhuozhi Gong, Jing He, Qiujian Feng, Wenyu Chen, Yonglong Xu, Qingying Wang, Shengjing Liu   +6 more
doaj   +1 more source

Comparative safety profile of biktarvy: insights from a clinical cohort and the FAERS database

Frontiers in Pharmacology
BackgroundBiktarvy, a second-generation integrase strand-transfer inhibitor, is approved for treating human immunodeficiency virus (HIV) in patients with no known resistance to its components.
Xinmei Pan, Qingqing Tian, Qian Wang, Linli Xie, Jiangchuan Xie   +4 more
doaj   +1 more source

Ivabradine, atrial fibrillation and stroke: a combined meta-analysis and FAERS disproportionality analysis

Frontiers in Pharmacology
Background Previous RCTs and meta-analyses observed an increased occurrence of atrial fibrillation (AF) associated with ivabradine use. Nonetheless, these studies were not focused on AF diagnosis, and it remains unclear whether this observed increase is due to a direct effect of ivabradine or just an augmented ...
Spadotto A., Fusaroli M., Carelli M., Nardi E., Amadori M., Massaro G., De Angelis V., Gatti M., Ciubine V., Raschi E., Poluzzi E., Diemberger I.   +11 more
openaire   +3 more sources

Drug-associated congenital anomalies of the external ear identified in the United States food and drug administration adverse event reporting system database

Scientific Reports
Congenital anomalies of the external ear can have a significant impact on a child’s development and quality of life. While genetic factors play a crucial role in the etiology of these anomalies, environmental factors such as drug exposure during ...
Xinyu Li, Jiajia Hao, Datao Li, Ruhong Zhang   +3 more
doaj   +1 more source