Results 111 to 120 of about 36,022 (292)
On the extraordinary : problematisation, flatness, and repetition [PDF]
, 2015 This essay reflects on the meaning and connotations of “the extraordinary” as applied to a person’s life context. To do so, it transposes to a smaller scale different concepts from philosophy of history (such as the notion of repetition in Nietzsche and ...
Mula Ferrer, Manel
core
Epidemiology of Primary Headache and Its Associated Psychosocial Factors Amongst Undergraduate Medical Students: A Cross-Sectional Study From the Vidarbha Region. [PDF]
Cureus, 2023 Sharma SK, Ukey UU.
europepmc +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
ConfluenzeThis article proposes a linguistic-textual analysis model inspired by the construal theory of Ronald W. Langacker, with its application in a study of four Chinese translations of the preface of the Book of Disquiet, posthumous work by Fernando Pessoa ...
Yujia Zhang
doaj +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
, 2022 The preservation of works of graphic design and their accompanying documentation is undoubtedly important, especially for a medium whose materiality is inherently ephemeral. But why is it that the graphic design archive continues to be dominated by an operative conception of the practice as a product of late-capitalist Global North industrial ...
openaire +1 more source
'All in good faith?' An ethno-historical analysis of local faith actors' involvement in the delivery of mental health interventions in northern Uganda. [PDF]
Transcult Psychiatry, 2023 Storer E, Torre C.
europepmc +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source