Results 71 to 80 of about 36,022 (292)

Paraneoplastic Lupus Nephritis in a Child With Neuroblastoma Recurrence

open access: yes
Pediatric Blood &Cancer, EarlyView.
Gabriele Mortari   +9 more
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Introduction [PDF]

open access: yes, 1981
Background: The importance of supportive business networks has been widely acknowledged in the field of entrepreneurship. Due to the success of informal business networks, the same networking concept is frequently encouraged and applied by regional ...
Hägnemark, Johan, Vilkelyte, Monika
core   +2 more sources

Māori education and principles of self-determination in the twenty-first century. [PDF]

open access: yes, 2001
This paper argues that self-determination to the greatest extent possible is a legitimate aspiration for Maori people. It is argued that in education this requires a philosophical and policy response more focused on Maori autonomy than can be provided ...
O’Sullivan, Dominic
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

THE 'SELF' AND 'THE BOOK OF DISQUIET': REFLECTIONS ON AUGUSTO DOS ANJOS AND FERNANDO PESSOA

open access: yesMatraga, 2014
This essay examines the poetry of Augusto dos Anjos through the concept of “fiction of disquiet”, borrowed from Fernando Pessoa, understood as a melancholic result from the modern tension between the construction of the ego and his intimacy, and the ...
Lucia Helena
doaj  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

[Review of the Book \u3ci\u3ePerspectives on American Labor History: The Problems of Synthesis\u3c/i\u3e] [PDF]

open access: yes, 1990
[Excerpt] Over the past two decades many claims have been made for what was once called the new labor history. Deeply influenced by European scholarship (especially by the British historian, E. P.
Salvatore, Nick
core   +1 more source

Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome

open access: yes
Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja   +8 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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