Isolated REM sleep behavior disorder is associated with altered 24-h rest-activity measures
IntroductionIsolated REM sleep behavior disorder (iRBD), the loss of motor inhibition during REM sleep, is a symptom of prodromal Lewy body disease, with over 80% of iRBD patients progressing to Parkinson's disease or dementia with Lewy bodies ...
Joseph R. Winer +9 more
doaj +1 more source
Circadian rest-activity rhythms predict cognitive function in early Parkinson's disease independently of sleep [PDF]
BACKGROUND: Cognitive impairment is a common and debilitating symptom of Parkinson's disease (PD), and its etiology is likely multifactorial. One candidate mechanism is circadian disruption. Although there is evidence of circadian abnormalities in PD, no
Cronin-Golomb, Alice +4 more
core +1 more source
Parent-Child Agreement in Report of Nighttime Respiratory Symptoms and Sleep Disruptions and Quality [PDF]
Asthma control requires assessment of nighttime symptoms and sleep disruption. Cognitive and emotional development enables most school-aged children to report nocturnal problems, but providers often rely only on parental report, potentially limiting the comprehensiveness of their assessments and their ability to support the child's emerging efforts at ...
Gail M, Kieckhefer +3 more
openaire +2 more sources
The neurobiology of circadian rhythms [PDF]
Purpose of review There is growing awareness of the importance of circadian rhythmicity in various research fields. Exciting developments are ongoing in the field of circadian neurobiology linked to sleep, food intake, and memory.
Boersma, Gretha J., +2 more
core +3 more sources
0438 Automatic Nighttime Agitation and Sleep Disruption Detection Using a Wearable Ankle Device and Machine Learning [PDF]
Abstract Introduction Nighttime agitation behavior such as wandering and restlessness during awake and sleep in people with Alzheimer’s disease (AD) is expensive to manage and adversely affects sleep. Nighttime agitation is mostly noted by subjective caregiver reports.
N Banerjee +8 more
openaire +1 more source
Voluntary exercise can strengthen the circadian system in aged mice [PDF]
Consistent daily rhythms are important to healthy aging according to studies linking disrupted circadian rhythms with negative health impacts. We studied the effects of age and exercise on baseline circadian rhythms and on the circadian system's ability ...
A Davidson +74 more
core +2 more sources
Sleep hygiene and environment are important for adequate sleep quantity and quality. We examined two aspects of the sleep environment, individual behaviors and ambient factors, with nighttime sleep parameters in pregnant women with insomnia.
semanticscholar +1 more source
Contemporary management of pain in cirrhosis: Toward precision therapy for pain
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman +4 more
wiley +1 more source
Behavioral Comorbidities and Drug Treatments in a Zebrafish scn1lab Model of Dravet Syndrome. [PDF]
Loss-of-function mutations in SCN1A cause Dravet syndrome (DS), a catastrophic childhood epilepsy in which patients experience comorbid behavioral conditions, including movement disorders, sleep abnormalities, anxiety, and intellectual disability.
Baraban, Scott C +2 more
core +1 more source
Shift Work: Gut Health and Metabolic Disease [PDF]
The number of people engaged in shift work continues to rise, and with it the research linking shift work to various diseases and conditions. Shift work changes the body’s sleeping patterns and circadian rhythms which has an effect on all parts of the ...
Lane, Hailey
core +1 more source

