Results 81 to 90 of about 43,835 (279)

The 9th International RASopathies Symposium

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The RASopathies are a group of congenital disorders with overlapping clinical manifestations that are caused by pathogenic germline or early somatic variants that result in the hyperactivation of the RAS/mitogen‐activated protein kinase (MAPK) signaling pathway.
Pau Castel, Lisa Schoyer, Beth Stronach, Raya Bogdanova, Anton M. Bennett, Jaishri Blakeley, Miriam Bornhorst, Tammy Bowers, Saskia M. Brachmann, Emma Burkitt‐Wright, Kathryn Chatfield, Alessandro De Luca, Khalil El‐Chammas, Abdul Elkadri, John E. Fortunato, Bruce D. Gelb, Anne Goriely, Karen Gripp, Kassidy Grover, Lindsay Homan, Kenneth A. Kern, Maija Kiuru, Charles (Chuck) Lawson, Yong‐Seok Lee, Frank McCormick, Gina Ney, Cristina Nuevo‐Tapioles, Sara Pardej, Elizabeth I. Pierpont, Julia Plank, Nancy Ratner, Katherine A. Rauen, J. Elliott Robinson, Les Rogers, Sarah E. Sheppard, Keir Shiels, David Stevenson, Dagmar Tiemens, Matthew Traylor, K. Nicole Weaver, Marielle Yohe, Tamar Green   +41 more
wiley   +1 more source

Rapid-eye-movement-sleep (REM) associated enhancement of working memory performance after a daytime nap [PDF]

, 2015
published_or_final_versio
Hui, FWY, Lau, EYY, Lau, KNT, Tseng, CH, Wong, ML   +4 more
core   +1 more source

Clock genes regulate Ca2+ signaling and mitochondrial bioenergetics to inhibit Sjogren's disease

Arthritis &Rheumatology, Accepted Article.
Objective Although Ca2+ signaling and metabolism have been identified as key determinants for the development of Sjogren's disease (SjD), the intricate connection between them and salivary gland physiology remains poorly understood. Methods Fluorescence‐based Ca2+ imaging, RNA seq, and mitochondrial activity were used to investigate the effects of ...
Viktor R. Drel, Manigandan Venkatesan, Rahul S. Jasrotia, Yuyang Sun, Viviane Nascimento Da Conceicao, Neelanjan Vishnu, Shankara N Varadarajan, Venugopal R. Bovilla, Rajender K Motiani, Shobhan Gaddameedhi, Bibhuti B. Mishra, Muniswamy Madesh, Brij B. Singh   +12 more
wiley   +1 more source

Household chaos and screen media use among preschool-aged children: a cross-sectional study

BMC Public Health, 2018
Background Excess screen media use is a robust predictor of childhood obesity. Understanding how household factors may affect children’s screen use is needed to tailor effective intervention efforts.
Jennifer A. Emond, Lucy K. Tantum, Diane Gilbert-Diamond, Sunny Jung Kim, Reina K. Lansigan, Sara Benjamin Neelon   +5 more
doaj   +1 more source

Endogenous melatonin partial metabolic clearance as a potential endogenous marker of CYP1A2 activity

British Journal of Clinical Pharmacology, EarlyView.
Aims Cytochrome P450 1A2 (CYP1A2) exhibits substantial interindividual variability, necessitating appropriate phenotyping strategies for personalized pharmacotherapy. This study evaluated endogenous melatonin partial metabolic clearance (CLm(MEL)), calculated from urinary 6‐hydroxymelatonin (6‐O‐MEL) excretion and plasma melatonin (MEL) exposure, as a ...
Akitomo Yokokawa, Hayato Shimazaki, Shunji Igarashi, Yoshiki Tagawa, Naoki Hisada, Hiromi Shibasaki   +5 more
wiley   +1 more source

Subjective Cognitive Decline and Nighttime Sleep Alterations, a Longitudinal Analysis

Frontiers in Aging Neuroscience, 2019
Objective: The aim of this study was to analyze quantitative sleep changes and their implication on subjective cognitive decline (SCD). Objective sleep patterns were investigated by an actigraph and recorded at the baseline and 2-year after in order to ...
G. Bubbico, A. Di Iorio, Mariella Lauriola, G. Sepede, S. Salice, E. Spina, Giacomo Brondi, Roberto Esposito, M. G. Perrucci, A. Tartaro   +9 more
semanticscholar   +1 more source

String Figuring young children's perspectives of quality in English early childhood education and care

British Educational Research Journal, EarlyView.
Abstract Quality in early childhood education and care (ECEC) is a contested concept and has generally been conceptualised by inter‐related indicators such as staff qualifications, educational environment, policy or child‐to‐staff ratios. There has been a more limited emphasis on how young children might perceive and experience quality.
Nikki Fairchild, Éva Mikuska
wiley   +1 more source

Acute sleep restriction effects on emotion responses in 30‐ to 36‐month‐old children [PDF]

, 2012
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/92066/1/j.1365-2869.2011.00962.x ...
Berger, Rebecca H., Cares, Stephanie R., Lebourgeois, Monique K., Miller, Alison L., Seifer, Ronald   +4 more
core   +1 more source

AI voice journaling for future language teachers: A path to well‐being through reflective practices

British Educational Research Journal, EarlyView.
Abstract This study aimed to explore the perceived impact of using an AI‐powered voice journaling app in overcoming the challenges and stressors encountered by senior students enrolled in teaching practicum at an English Language Teaching Bachelor's programme.
Bora Demir, Duygu Özdemir
wiley   +1 more source

Integrating an Eco-Feedback Strategy to Enhance the Indoor Environmental Quality and Sleep Quality in Italian Bedrooms

Buildings
This study examines the short-term impact of an “eco-feedback” strategy, based on an awareness-raising information campaign and an experimental campaign, on indoor environmental quality (IEQ) parameters and sleep quality in Italian bedrooms.
Michael T. Solomon, Laura Canale, Luca Stabile, Anderson D’Oliveira, Alexandro Andrade, Giorgio Buonanno   +5 more
doaj   +1 more source