Results 211 to 220 of about 2,396,820 (308)

Investigating interbrain synchrony under teamwork disruption: an fNIRS hyperscanning study. [PDF]

Behav Brain Funct
Réveillé C, Vergotte G, Dray G, Jean PA, Jean P, Pla S, Perrey S, Bosselut G.   +7 more
europepmc   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Corrigendum to “Recent increased incidence of invasive serogroup W meningococcal disease: A retrospective observational study” [International Journal of Infectious Diseases, 108 (2021), 582-587]

International Journal of Infectious Diseases
Nichlas Hovmand, Lene Fogt Lundbo, Gitte Kronborg, Sidsel Skou Voss, Håkon Sandholdt, Steen Hoffmann, Palle Valentiner-Branth, Thomas Benfield   +7 more
doaj   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Functional brain connectivity in patients with <i>de novo</i> Parkinson's disease. [PDF]

Neuroimage Rep
Picchi E, Minosse S, Pucci N, Conti M, Mascioli D, Stefani A, Garaci F, Ferrazzoli V, Da Ros V, Schirinzi T, Di Giuliano F.   +10 more
europepmc   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Circadian rhythms and microbiota: molecular crosstalk and its implications for health and disease. [PDF]

Biol Direct
Wu G, Zhang J, Yan S, Liu N, Chen W, Wu F, Wang Z, Zhang J, Yang Y, Deng Y, Qiu X, Liu J, Shi L, Cui X, Wan R, Li X, Han Y, Yang G.   +17 more
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Visualization of gadolinium transport across the blood-brain barrier along perivascular clearance pathways. [PDF]

Eur Radiol Exp
Seehafer S, Mrosek Y, Schmill LP, Aludin S, Jansen O, Gless CA, Rümenapp J, Larsen N.   +7 more
europepmc   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source