Results 71 to 80 of about 2,381,058 (285)
Predictable Disruption Tolerant Networks and Delivery Guarantees [PDF]
This article studies disruption tolerant networks (DTNs) where each node knows the probabilistic distribution of contacts with other nodes. It proposes a framework that allows one to formalize the behaviour of such a network. It generalizes extreme cases
A. Lindgren +8 more
core +3 more sources
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
The research investigates the role of leadership in the transformation of denominational structures towards a missional ecclesiology, and focusses on the Highveld Synod of the Dutch Reformed Church. It describes the missional journey of the denomination,
C.J.P. (Nelus) Niemandt
doaj +1 more source
Spectroscopic Signatures of the Tidal Disruption of Stars by Massive Black Holes
During the tidal disruption of a star by a massive black hole (BH) of mass MBH
Balcells +37 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Travel Disruption: Three Case Studies [PDF]
This report draws together the findings of three studies of travel disruption and its impacts on travellers: the volcanic ash cloud which disrupted aviation in Europe in 2010, the loss of road bridges between November 2009 and April 2010 at Workington ...
Disruption Project, Guiver, Jo W
core
DIP: Disruption-Tolerance for IP [PDF]
Disruption Tolerant Networks (DTN) have been a popular subject of recent research and development. These networks are characterized by frequent, lengthy outages and a lack of contemporaneous end-to-end paths.
Neufeld, Michael
core
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Linguistic Interventions and Transformative Communicative Disruption [PDF]
What words we use, and what meanings they have, is important. We shouldn't use slurs; we should use 'rape' to include spousal rape (for centuries we didn’t); we should have a word which picks out the sexual harassment suffered by people in the workplace ...
Sterken, Rachel Katharine
core
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source

