Results 51 to 60 of about 193,431 (315)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The diffusion of IP telephony and vendors' commercialisation strategies [PDF]

open access: yes, 2009
This is a post-peer-review, pre-copyedit version of an article published in the Journal of Information Technology. The definitive publisher-authenticated version is available at the link below.The Internet telephony (IP telephony) has been presented as a
Dwivedi, YK   +2 more
core   +1 more source

The Day of Prayer and Its Potential for Engendering Public Ecclesiology Ecumenism in Zambia

open access: yesReligions, 2018
This article argues that while the National Day of Prayer in Zambia has its inception in political context, it has obligated the institutional churches to break out of their religiously fixed spaces, forcing them to suspend their official doctrinal ...
Chammah J. Kaunda
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

War and peace in the classroom: moments of reprieve; a strategy for reflecting on – and improving – students’ classroom behaviour

open access: yes, 2013
In this article I intend to outline a strategy for supporting trainee teachers on Certificate in Education (Cert Ed) and Postgraduate Certificate in Education (PGCE) courses in developing their ability to deal with disruptive student behaviour in their ...
Lebor, Merv
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

The Effectiveness of Functioning as a Robust Systems and Using Relational Leadership to Enhance Disruptive Innovation in Small and Medium Enterprises(SMEs)

open access: yes, 2021
This paper investigates the role that Relational Leadership and Robust Systems theory play in the enhancement of Disruptive Innovation in Small and Medium Enterprises (SMEs).
ALMALOY, Yasser, Almaloy,, Y.
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Phase-change perovskite metasurfaces for dynamic color tuning

open access: yesNanophotonics, 2022
Halide perovskite metasurfaces are attracting increasing interest for applications in light-emitting and display technologies. To access the wide range of colors required for these applications, the main mechanism exploited thus far has been chemical ...
Tian Jingyi   +7 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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