Results 61 to 70 of about 122,020 (295)

The prevalence of impulsive compulsive behaviors in patients treated with apomorphine infusion: a retrospective analysis

Arquivos de Neuro-Psiquiatria, 2021
Background: Impulsive compulsive behaviors (ICBs) can affect a significant number of Parkinson’s disease (PD) patients. Objective: We have studied brain samples from a brain bank of PD patients who received apomorphine via continuous infusion in life to
Pedro Barbosa, Atbin Djamshidian, Andrew John Lees, Thomas Treharne Warner   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Validation of a cross-cultural instrument for child behavior problems: the Disruptive Behavior International Scale – Nepal version

BMC Psychology, 2018
Background Obtaining accurate and valid measurements of disruptive behavior disorders remains a challenge in non-Western settings due to variability in societal norms for child behavior and a lack of tools developed outside of Western contexts.
Matthew D. Burkey, Ramesh P. Adhikari, Lajina Ghimire, Brandon A. Kohrt, Lawrence S. Wissow, Nagendra P. Luitel, Emily E. Haroz, Mark J. D. Jordans   +7 more
doaj   +1 more source

Yoga and Its Influence on Children\u27s Behavior [PDF]

, 2018
This study looked at the impact ten minutes of daily yoga had on the behavior of elementary school children. Yoga was led by classroom teachers once daily for ten minutes over a sixteen-week period.
Sellen, Paige
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Activation of 5-HT 2A Receptor Disrupts Rat Maternal Behavior [PDF]

, 2019
Serotonin 5-HT2A receptor is widely distributed in the central nervous system and plays an important role in sensorimotor function, emotion regulation, motivation, executive control, learning and memory. We investigated its role in rat maternal behavior,
Davis, Collin, Gao, Jun, Li, Ming, Wu, Ruiyong   +3 more
core   +1 more source

School Violence Prevention: Evaluating a Cognitive-Behavioral Intervention for Aggression Among Adolescents [PDF]

, 2020
Schools are held accountable for creating and maintaining safe learning environments for all students. The prevalence of behavior and conduct disorders, specifically aggression, remain problematic for school campuses.
Katic, Barbara
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Clinical profile and outcome in a large sample of children and adolescents with obsessive–compulsive disorder: A chart review from a tertiary care center in India

Indian Journal of Psychiatry, 2018
Background: Obsessive–compulsive disorder (OCD) is a common psychiatric illness in children and adolescents. Till date, the sample sizes in the Indian studies have been relatively small. Methodology: The present study is a retrospective chart review of a
K. Deepthi, John Vijay Sagar Kommu, M. Smitha, Y. C. Janardhan Reddy   +3 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source