Results 71 to 80 of about 122,020 (295)

Influence of Genetic Variants of the N-Methyl-D-Aspartate Receptor on Emotion and Social Behavior in Adolescents

Neural Plasticity, 2016
Considerable evidence has suggested that the epigenetic regulation of N-methyl-D-aspartate (NMDA) glutamate receptors plays a crucial role in neuropsychiatric disorders. Previous exploratory studies have been primarily based on evidence from patients and
Li-Ching Lee, Ying-Chun Cho, Pei-Jung Lin, Ting-Chi Yeh, Chun-Yen Chang, Ting-Kuang Yeh   +5 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Psychopathology, trauma and delinquency: subtypes of aggression and their relevance for understanding young offenders

Child and Adolescent Psychiatry and Mental Health, 2011
Objective To examine the implications of an ontology of aggressive behavior which divides aggression into reactive, affective, defensive, impulsive (RADI) or "emotionally hot"; and planned, instrumental, predatory (PIP) or "emotionally cold." Recent ...
Plattner Belinda, Huemer Julia, Karnik Niranjan S, Silverman Melissa, Steiner Hans, Clark Christina E, Blair James R, Haapanen Rudy   +7 more
doaj   +1 more source

Desenho em série com meninas que apresentam comportamento oposicionista desafiante em sala de aula [PDF]

, 2015
Este estudio investigó las correlaciones entre la participación en sesiones terapéuticas de dibujo en serie, no dirigido, y la presencia o ausencia de mejoría en el comportamiento oposicionista desafiante (COD) de cinco niñas, de ocho a diez años de edad,
Boone-Salles, Andréia Mansk
core   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Validity of the multidimensional assessment profile of disruptive behavior in autistic toddlers

JCPP Advances
Objective Early measurement of atypical disruptive behavior within autistic children is critical for later referrals to behavioral screenings, diagnoses, and services.
Hannah Fipp‐Rosenfield, Jeffrey Grauzer, Megan Y. Roberts, Aaron J. Kaat   +3 more
doaj   +1 more source

Nitric Oxide Levels in Disruptive Behavioral Disorder

Neuropsychobiology, 2006
There are various evidences of the role of nitric oxide (NO) in several neuropsychiatric disorders. However, there is no clinical study which investigated the role of NO in disruptive behavioral disorders (DBD). The aim of this study is to investigate the relation between NO levels and DBD. NO levels were measured in serum from 45 patients diagnosed as
Taş, Fatma Varol, Güvenir, Taner, Taş, Gültekin, Ormen, Murat, Çakaloz, Burcu   +4 more
openaire   +7 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Prevalence of psychiatric comorbidities and treatment initiation in African American pediatric patients with vitiligo: A retrospective, single-center, case-control studyCapsule Summary

JAAD International
Background: Vitiligo may impact psychosocial development, especially among African American pediatric patients, given heightened visibility and increasing rates of anxiety and depression in this subpopulation.
Emily Strouphauer, BSA, Sana Suhail, BS, Carly Mulinda, BA, Promise Ufomadu, BSA, Nicole Nyamongo, BS, Grace Lee, MD, Soo Jung Kim, MD, PhD   +6 more
doaj   +1 more source

Headache and alexithymia in children and adolescents: what Is the connection? [PDF]

, 2018
Background: Headache is one of the most common complaints in children and adolescents and comorbidity rates are very high and the major associated diseases are depression, anxiety, atopic disorders, sleep, and behavioral disorders.
Calderoni, D, Cerutti, R, Faedda, N, Guidetti, V., Natalucci, G, Verdecchia, P   +5 more
core   +3 more sources