Results 91 to 100 of about 77,934 (284)

Symptomatic central nervous system tuberculoma, a case report in the United States and literature review [PDF]

open access: yes, 2019
Intracranial tuberculoma is one of the rare central nervous system manifestations of Mycobacterium tuberculosis (MTB), seen in only 1% of tuberculosis patients.
Butt, Saira, Mohammadian, Mahsa
core   +1 more source

The role of the A C395 IFNGR1 mutation in determining susceptibility to intracellular infection in Malta [PDF]

open access: yes, 2012
Background: The first human mycobacterial susceptibility gene was identified amongst four children on the island of Malta in 1995. All affected children were homozygous for a nonsense mutation at position 395 of the interferon gamma receptor 1 (IFNGR1 ...
Anderson, Suzanne T.   +6 more
core  

Infectious Diseases Associated With Renal Homotransplantation: I. Incidence, Types, and Predisposing Factors [PDF]

open access: yes, 1964
Infectious diseases occurred in 26 of 30 renal homotransplantation patients and contributed to eight of the 12 deaths in this series. There were 52 infections, 17 occurring before and 35 after transplantation.
Marchioro, TL   +3 more
core   +1 more source

Contributions of Community Advisory Board and Experience of Study Participants in TB/MDR‐TB Clinical Trial Management in Addis Ababa, Ethiopia: A Qualitative Study

open access: yesDeveloping World Bioethics, EarlyView.
ABSTRACT Community Advisory Boards (CABs), as a form of community engagement, provide an important mechanism to ensure that research aligns with community needs and priorities by representing broader community interests and guiding research accordingly.
Yemisrach Seralegne   +4 more
wiley   +1 more source

Lung organoids as a human system for Mycobacteria infection modeling and drug testing

open access: yesThe FEBS Journal, EarlyView.
Mycobacterial infections, including tuberculosis (TB) and infections by nontuberculous mycobacteria (NTM), are still public health issues. In 2023, TB caused 1.25 million deaths, while NTM remain a clinical challenge for patients with cystic fibrosis (CF).
Stephen Adonai Leon‐Icaza   +4 more
wiley   +1 more source

Concurrent multiple brain tuberculomas with miliary tuberculosis - A rare presentation

open access: yesAsian Journal of Medical Sciences, 2014
A 45 year old immunocompetent female presented to us with fever, dry cough, vomitingand headache. There was a single episode of convulsion after hospital admission. ChestXray was normal.
Susmita Kundu
doaj   +1 more source

The Dual Immunoregulatory Role of CREB3L1 Underlying Latent and Severe Tuberculosis Clinical Manifestation

open access: yesImmunology, EarlyView.
RNA‐seq of lungs and livers from Mycobacterium tuberculosis‐infected mice with distinct disease outcomes revealed organ‐specific responses driven by differences in immune activity and bacterial burden. Meta‐analysis identified orthologous genes shared with human latent TB and mouse liver, with Creb3l1, Myo7b, Cyyr1 and Cbs differentially expressed and ...
Felipe T. Lima   +9 more
wiley   +1 more source

Profound peripheral T-lymphocyte depletion and activation in disseminated tuberculosis

open access: yesBrazilian Journal of Infectious Diseases
Three HIV-1-seronegative patients with disseminated tuberculosis presented significant depletion of T-cell counts, in CD4+ and/or CD8+ cells, associated with increased expression of activation marker CD38 on CD8+ T-lymphocytes.
Denise Silva Rodrigues   +2 more
doaj   +1 more source

Evaluation of Xpert® MTB/RIF and ustar easyNAT™ TB IAD for diagnosis of tuberculous lymphadenitis of children in Tanzania : a prospective descriptive study [PDF]

open access: yes, 2016
Fine needle aspiration biopsy has become a standard approach for diagnosis of peripheral tuberculous lymphadenitis. The aim of this study was to compare the performance of Xpert MTB/RIF and Ustar EasyNAT TB IAD nucleic acid amplification assays, against ...
AT Cruz   +39 more
core   +3 more sources

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