Results 71 to 80 of about 437,253 (247)

Precision immunomodulation for pediatric hemophagocytic lymphohistiocytosis in intensive care

Pediatric Investigation, EarlyView.
This review presents a bedside framework for recognizing pediatric hemophagocytic lymphohistiocytosis and cytokine storm, stabilizing organ dysfunction, identifying the underlying phenotype, selecting targeted immunomodulation, considering extracorporeal adjuncts, and reassessing response within 24–72 h. ABSTRACT Hemophagocytic lymphohistiocytosis (HLH)
Weerapong Lilitwat, Prakreeti Bhandari
wiley   +1 more source

Advancing pharmacometrics in Africa—Transition from capacity development toward job creation

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 407-419, March 2025.
Abstract Trained pharmacometricians remain scarce in Africa due to limited training opportunities, lack of a pharmaceutical product development ecosystem, and emigration to high‐income countries. The Applied Pharmacometrics Training (APT) fellowship program was established to address these gaps and specifically foster job creation for talent retention.
Goonaseelan (Colin) Pillai, Samer Mouksassi, Innocent G. Asiimwe, Craig R. Rayner, Steven Kern, Phumla Sinxadi, Paolo Denti, Eric Decloedt, Catriona Waitt, Bernhards R. Ogutu, Rik de Greef   +10 more
wiley   +1 more source

Necessity to screen and treat latent tuberculosis before ruxolitinib treatment—Ruxolitinib-associated disseminated tuberculosis: A case report and literature review

IDCases, 2020
Ruxolitinib, a Janus kinase inhibitor, considerably improves symptoms of patients with polycythemia vera and primary or secondary myelofibrosis. However, its association with the development of infectious complications is a concern. Herein, we report the
Nobuyasu Hirai, Kei Kasahara, Shingo Yoshihara, Tomoko Nishimura, Keitaro Omori, Yoshihiko Ogawa, Taku Ogawa, Naokuni Hishiya, Yuki Suzuki, Hisakazu Yano, Masahide Yoshikawa, Keiichi Mikasa   +11 more
doaj   +1 more source

Dosing HIV integrase inhibitors with enzyme inducers: Convenience vs. control?

British Journal of Clinical Pharmacology, EarlyView.
Catia Marzolini, Saye Khoo
wiley   +1 more source

Temporal and seasonal trends of bovine tuberculosis in the Irish cattle population (2008–2024)

Veterinary Record, EarlyView.
Abstract Background Bovine tuberculosis (bTB) has substantial impacts on the Irish cattle industry. Between 2016 and 2024, its burden increased in Irish cattle. As an initial step towards understanding drivers of this increase, we explore long‐term trends in measures of bTB burden and cattle demographics in Ireland. Methods Using data from 2008 to 2024,
Jamie M. Madden, Eamonn Gormley, Philip Breslin, Damien Barrett, Jonas Brock, Jamie A. Tratalos, John Griffin, Mike Horan, Miriam Casey‐Bryars   +8 more
wiley   +1 more source

‘The Tragedy of a Small Nation’: Alexander Devine and British Perspectives on the Montenegrin Question, 1918–24

History, EarlyView.
Abstract This article examines the pro‐Montenegrin political campaigns of Alexander Devine, a schoolmaster and journalist who became Montenegro's leading British advocate following its incorporation into the Kingdom of Serbs, Croats and Slovenes after the First World War.
ROSS CAMERON
wiley   +1 more source

Disseminated tuberculosis following BCG vaccination

, 2014
Disseminated tuberculosis is rare in infants. The more common presentations of tuberculosis (TB) in infancy include pulmonary and meningeal involvement.
Bjc Perera, J Senevirathna, Cs Perera, Krcp Kekulawala   +3 more
core  

Tuberculosis diagnosis using immunodominant, secreted antigens of Mycobacterium tuberculosis [PDF]

, 2013
Summary Tuberculosis (TB) remains a major public health concern in most low-income countries. Hence, rapid and sensitive TB diagnostics play an important role in detecting and preventing the disease. In addition to established diagnostic methods, several
Aliya, Bekmurzayeva, Sypabekova, Marzhan, Kanayeva, Damira, Bekmurzayeva, Aliya   +3 more
core   +1 more source

TOXOPLASMOSIS CEREBRAL EN UN PACIENTE CON SIDA Y RECIDIVA DE HIPERINFESTACIÓN POR STRONGYLOIDES STERCORALIS Y TUBERCULOSIS DISEMINADA

Revistas Argentina de Medicina, 2017
El pronóstico de los pacientes con sida depende del éxito del tratamiento antirretroviral. El curso clínico de la inmunodeficiencia severa sin tratamiento antirretroviral eficaz favorece la aparición de infecciones oportunistas y de sus recidivas ...
Luis Trombetta, Guillermo Onis, Karin Semorile, Dora Pugliese, Cristian Castellón Gutiérrez, Amadeo Javier Bava   +5 more
doaj   +2 more sources

Hemophagocytic Lymphohistiocytosis as a Complication of Peritoneal Dialysis–Associated Peritonitis and Miliary Tuberculosis

Annals of Internal Medicine: Clinical Cases
We report a unique case of peritoneal dialysis (PD)–associated peritonitis secondary to disseminated tuberculosis that was complicated by hemophagocytic lymphohistiocytosis.
Tanya Geranpayeh, John C. Schwartz, Sridhar Badireddi, Reynaldo B. Daba, Robyn M. Olney, Asha J. Chemmalakuzhy   +5 more
doaj   +1 more source