Results 51 to 60 of about 437,253 (247)

Deucravacitinib in Active Psoriatic Arthritis: Efficacy and Safety Up to 52 Weeks From the Randomized, Double‐Blind, Phase 3 POETYK PsA‐2 Trial

open access: yesArthritis &Rheumatology, EarlyView.
Objective To assess the efficacy and safety of deucravacitinib, an oral, selective tyrosine kinase 2 inhibitor, in patients with psoriatic arthritis (PsA) who were naive to biologic disease‐modifying antirheumatic drugs or received tumor necrosis factor inhibitors. Methods In the 52‐week, double‐blind, placebo‐controlled, phase 3 Program for Evaluation
Philip J. Mease   +20 more
wiley   +1 more source

Human tuberculosis - an ancient disease, as elucidated by ancient microbial biomolecules [PDF]

open access: yes, 2009
Tuberculosis is a major cause of death but infected people with effective immunity may remain healthy for years, suggesting long-term coexistence of host and pathogen.
Donoghue, HD, Helen D. Donoghue
core   +1 more source

Disseminated tuberculosis in an immunocompetent healthy young male with nonspecific symptoms: challenges toward diagnosis—a case report

open access: yesJournal of Medical Case Reports
Background Disseminated tuberculosis, characterized by spread of Mycobacterium tuberculosis to multiple noncontiguous sites, is rare in immunocompetent individuals.
Md Abdullah Al Maruf   +3 more
doaj   +1 more source

Chest pain and a left parasternal soft tissue swelling in an immunocompetent refugee with disseminated tuberculosis

open access: yesInternational Journal of Infectious Diseases, 2020
An immunocompetent migrant with chest pain was admitted to an Italian hospital. Computed tomography showed a left pectoral abscess and osteomyelitis of the sternum.
Michele Mondoni   +9 more
doaj   +1 more source

A case of disseminated tuberculosis mimicking metastatic cancer

open access: yesRespiratory Medicine Case Reports, 2018
Background: Disseminated tuberculosis (TB) or miliary TB is defined as lymphohematogenous dissemination of Mycobacterium tuberculosis bacilli, which may then affect virtually any organ system.
K. Chamberlin   +5 more
doaj   +1 more source

Severity of maternal anemia and the risk of giving birth to a small vulnerable newborn: A cohort analysis of the WOMAN‐2 trial in four countries

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To investigate the association between maternal hemoglobin concentration and the risk of birth to a small vulnerable newborn (SVN). Methods We conducted a cohort analysis of women with moderate or severe anemia enrolled in the World Maternal Antifibrinolytic Trial‐2 (WOMAN‐2) across Nigeria, Pakistan, Tanzania, and Zambia (August ...
Henry Ochola   +114 more
wiley   +1 more source

Organ‐Resolved Host Proteomic and Post‐Translational Modification Landscapes in a Mouse Model of Talaromyces marneffei Infection

open access: yesiMetaMed, EarlyView.
We presented an organ‐resolved, multiple PTM remodeling atlas of systemic T. marneffei infection, integrating quantitative proteome, phosphoproteome, ubiquitinome, acetylome, and lactylome data across the liver, lung, and spleen. The atlas delineated organ‐specific PTM signatures and a functional convergence of divergent modification types on immune ...
Wudi Wei   +16 more
wiley   +1 more source

Multisystemic tuberculosis: An unusual form of presentation

open access: yesIatreia, 2015
Worldwide, tuberculosis is still an important cause of illness and death among children. They are particularly vulnerable to this disease when it is disseminated and severe.
Sepúlveda-Otálvaro, Cristian   +2 more
doaj   +1 more source

Disseminated tuberculosis with immune thrombocytopenic purpura

open access: yes, 2012
Tuberculosis has a variety of hematological manifestations. Immune thrombocytopenic purpura is an uncommon manifestation of tuberculosis. We present a case of disseminated tuberculosis with isolated thrombocytopenia.
Zarir F Udwadia, Rucha S Dagaonkar
core   +1 more source

Tuberculosis of the foot and ankle in children [PDF]

open access: yes, 2011
The purpose of our retrospective study is to critically assess the long-term outcome of tuberculosis of the foot and ankle in children and to define an initial classification system that would relate to ...
Maqungo, Sithombo
core   +1 more source

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