Results 51 to 60 of about 77,934 (284)

Public health advocacy for the Berlin Declaration on tuberculosis in the former Soviet Union: the view of Médecins Sans Frontières [PDF]

, 2012
To assist international efforts to address major gaps in the availability and accessibility of quality diagnosis and treatment for multi-drug resistant tuberculosis, Médecins Sans Frontières has adapted an approach combining three sets of interlinked ...
Balabanova D., Bonnet M., Brust J.C., Cox H.S., Cox H.S., Cox H.S., Majumdar S.   +6 more
core   +2 more sources

A cooperative release of mitochondrial DNA from platelets and neutrophils drives an interferon signature in systemic sclerosis

Arthritis &Rheumatology, Accepted Article.
Objective Mitochondria are organelles with a hypomethylated circular genome. Mitochondrial DNA (mtDNA) in the systemic circulation has been implicated in inflammation. This study investigates the role of circulating DNA in systemic sclerosis (SSc) and the cellular mechanisms governing its release.
Stavros Giaglis, André N. Tiaden, Simone Häner‐Massimi, Diego Kyburz, Cedric André, Anton Glück, Enrico Ferrero, Stuart Hawtin, Tobias Junt, Ulrich A. Walker   +9 more
wiley   +1 more source

Chest pain and a left parasternal soft tissue swelling in an immunocompetent refugee with disseminated tuberculosis

International Journal of Infectious Diseases, 2020
An immunocompetent migrant with chest pain was admitted to an Italian hospital. Computed tomography showed a left pectoral abscess and osteomyelitis of the sternum.
Michele Mondoni, Marco Centola, Ottavia Viganò, Maurizio Ferrarese, Luigi Codecasa, Antonella D’Arminio Monforte, Stefano Carugo, Stefano Centanni, Marc Lipman, Giovanni Sotgiu   +9 more
doaj   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source

Infection Risk From Humans and Animals in the Anatomy Laboratory: A Scoping Review

Clinical Anatomy, EarlyView.
ABSTRACT Whole‐body dissection is a cornerstone of anatomy education. During and following the COVID‐19 pandemic, exposure to infectious agents and other risks of dissection were highlighted. To identify potential risks, one must have the data outlining these risks in specific situations.
Margaret A. McNulty, Elizabeth R. Agosto
wiley   +1 more source

Multisystemic tuberculosis: An unusual form of presentation

Iatreia, 2015
Worldwide, tuberculosis is still an important cause of illness and death among children. They are particularly vulnerable to this disease when it is disseminated and severe.
Sepúlveda-Otálvaro, Cristian , Morales-Múnera, Olga Lucía , Palacio-Petri, Silvia   +2 more
doaj   +1 more source

Comparing research investment to United Kingdom institutions and published outputs for tuberculosis, HIV and malaria: A systematic analysis across 1997-2013 [PDF]

, 2015
Background: The "Unfinished Agenda" of infectious diseases is of great importance to policymakers and research funding agencies that require ongoing research evidence on their effective management.
A Aghaei Chadegani, Benjamin Beattie, Christopher J. Counts, Fatima B. Wurie, G Fätkenheuer, GBD 2013 Mortality and Causes of Death Collaborators, Gemma Derrick, Global Burden of Disease Study 2013 Collaborators, Health Economics Research Group, Office of Health Economics, RAND Europe, J Iñigo, Jonathan Meldrum, Joseph R. Fitchett, JR Fitchett, K Bourzac, K Jonkers, M Glover, MG Head, MG Head, MG Head, MG Head, Michael G. Head, ML Rethlefsen, Nina Kumari, P Cures, P Vinkler, Q Yao, Rifat Atun, S Wooding, S Wooding, SLM Davis, TC Ha, World Health Organization   +31 more
core   +7 more sources

PharmVar GeneFocus: NAT2—Genetic Variation and Updated Nomenclature

Clinical Pharmacology &Therapeutics, EarlyView.
The Pharmacogene Variation Consortium (PharmVar) provides nomenclature for the highly polymorphic human N‐acetyltransferase 2 (NAT2) gene. NAT2 metabolizes several clinically used drugs including isoniazid, hydralazine, amifampridine, procainamide, and sulfonamides such as dapsone, and also some highly carcinogenic arylamines.
Georgia Papanikolaou, Estella S. Poloni, José A.G. Agúndez, Raquel L.F. Teixeira, Erin C. Boone, Adalberto Rezende Santos, Michelle Whirl‐Carrillo, Katrin Sangkuhl, Teri E. Klein, Mariam R. Habil, Giannoulis Fakis, Rodney F. Minchin, David W. Hein, Sotiria Boukouvala, Andrea Gaedigk   +14 more
wiley   +1 more source

A case of disseminated tuberculosis mimicking metastatic cancer

Respiratory Medicine Case Reports, 2018
Background: Disseminated tuberculosis (TB) or miliary TB is defined as lymphohematogenous dissemination of Mycobacterium tuberculosis bacilli, which may then affect virtually any organ system.
K. Chamberlin, S. Orfanos, A. Mukherjee, E. Moy, M. Koganti, W. Khan   +5 more
doaj   +1 more source

Lymph‐based liquid biopsy: Current progress and future potential

Interdisciplinary Medicine, EarlyView.
Recent evidence under the revised Starling principle indicates that lymph‐based liquid biopsies may offer superior diagnostic performance over blood‐based counterparts in certain clinical scenarios, such as early‐stage solid tumor detection. Currently, various biomarkers within the lymphatic system show significant diagnostic potential for a range of ...
Dongdong Liu, Leheng Cheng, Xiaolin Hu, Sergio Bernardini, Hong Zhang, Ling Zhu, Yang Luo   +6 more
wiley   +1 more source