Results 81 to 90 of about 1,052,737 (342)

Harnessing the Biological Responses Induced by Nanomaterials for Enhanced Cancer Therapy

open access: yesAggregate, EarlyView.
Nanomaterial (NM)‐induced toxicity can be strategically repurposed for cancer therapy. This review summarizes the mechanism by which NMs selectively activate specific cellular processes to regulate cell fate independently. We also discussed how NMs‐induced biological responses can be leveraged as therapeutic strategies for cancer treatment.
Liting Wang   +6 more
wiley   +1 more source

Intelligent Theranostic Systems Enabled by Aggregation‐Induced Emission in Precision Medicine

open access: yesAggregate, EarlyView.
Aggregation‐induced emission (AIE) luminogens are driving a new generation of intelligent theranostic systems that integrate high‐fidelity imaging and multifunctional therapy. This review highlights how AIEgens, through restriction of intramolecular motion (RIM), enable deep‐tissue NIR‐II imaging, ultrasensitive biosensing, CRISPR‐assisted gene ...
Qinqin Huang   +7 more
wiley   +1 more source

Risk factors for drug resistant tuberculosis in Leicestershire - poor adherence to treatment remains an important cause of resistance [PDF]

open access: yes, 2013
In the light of rising numbers of tuberculosis (TB) cases in the United Kingdom, the problem of anti-tubercular drug resistance remains a significant concern.
Hayward, AC   +3 more
core   +2 more sources

The hidden hypothesis: A disseminated tuberculosis case [PDF]

open access: yesInternational Journal of Infectious Diseases, 2019
77-year-old former smoker admitted because of fatigue and abdominal distention. Past medical history positive for two previous hospitalizations for pericardial and pleural effusions (no diagnosis achieved). At admission erythrocyte sedimentation rate was 122mm per hour.
Foresti S.   +8 more
openaire   +4 more sources

Linezolid for Infants and Toddlers With Disseminated Tuberculosis: First Steps

open access: yesClinical Infectious Diseases, 2016
Background. Infants and toddlers often present with disseminated and lymph node tuberculosis, in which Mycobacterium tuberculosis (Mtb) is predominantly intracellular.
D. Deshpande   +6 more
semanticscholar   +1 more source

Effect of Long‐Term Voclosporin Treatment on Renal Histology in Patients With Active Lupus Nephritis With Repeat Renal Biopsies

open access: yesArthritis &Rheumatology, EarlyView.
Objective This study characterized the impact of voclosporin on kidney histology in patients with lupus nephritis (LN) who had protocolized repeat kidney biopsies in the AURORA clinical trials. Methods Patients were randomized to voclosporin or placebo treatment for up to 3 years; all patients received mycophenolate mofetil and low‐dose glucocorticoids.
Brad H. Rovin   +9 more
wiley   +1 more source

High‐throughput exosomes analysis for ovarian cancer screening based on a double‐positive surface marker detection biochip

open access: yesBMEMat, EarlyView.
A double‐positive surface marker detection approach was developed to conduct exosome surface protein detection in serum samples. It reaches single‐exosome detection, and over 300 exosome protein parameters are analyzed. The diagnostic accuracy achieved 90% in differentiation of high‐grade serous/serous ovarian carcinoma patients, benign patients, and ...
Jiaoyan Qiu   +7 more
wiley   +1 more source

Atypical Presentation of Disseminated Tuberculosis

open access: yesJournal of the Royal College of Physicians of Edinburgh, 2020
Disseminated Tuberculosis is a potentially lethal disease if not diagnosed and treated early. Therefore a high index of clinical suspicion for early diagnosis and timely institution of anti-tuberculosis treatment is important. We report a case of an elderly female who presented with complaints of weight loss, generalised fatigue, altered sensorium and
Praveen Valsalan   +3 more
openaire   +3 more sources

Disseminated Tuberculosis among Adult Patients Admitted to Hamad GeneralHospital, Qatar: A Five Year Hospital Based Study

open access: yes, 2016
Objectives: To describe the demographic, clinical features, diagnostic and procedure results, organ involvement and outcomes in patients with disseminated tuberculosis (TB).
F. Khan   +7 more
semanticscholar   +1 more source

Disseminated Tuberculosis

open access: yesSiriraj Medical Journal, 2002
Tuberculosis usually causes symptoms. Many patients may first be aware of fatigue, anorexia, weight loss, irregular menses, or a low grade fever that persists over weeks to months.
Suwanit Therasakvichya   +4 more
doaj  

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