Results 81 to 90 of about 1,769,169 (305)

Liquid Journals: Knowledge Dissemination in the Web Era [PDF]

open access: yes, 2010
In this paper we redefine the notion of "scientific journal" to update it to the age of the Web. We explore the historical reasons behind the current journal model, and we show that this model is essentially the same today, even if the Web has made ...
Baez, Marcos   +3 more
core  

Age Optimal Information Gathering and Dissemination on Graphs

open access: yes, 2019
We consider the problem of timely exchange of updates between a central station and a set of ground terminals $V$, via a mobile agent that traverses across the ground terminals along a mobility graph $G = (V, E)$.
Modiano, Eytan   +2 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

A randomized, controlled, pragmatic trial of an iPad-based, tailored messaging intervention to increase human papillomavirus vaccination among Latinos

open access: yesHuman Vaccines & Immunotherapeutics, 2019
Human papillomavirus (HPV) causes a number of cancers that disproportionally affect Latinos yet there is a paucity of research on interventions to increase HPV vaccination among this population.
Amanda F. Dempsey   +4 more
doaj   +1 more source

Rift Valley Fever : processes of emergeance and dissemination [PDF]

open access: yes, 2009
Risk factors of Rift Valley fever (RVF) emergence remain partially unknown [1]. RVF is endemic in the Ferlo area (northern Senegal).A serological study performed in this region in small ruminants associated with an entomological study showed that the ...
Chevalier, Véronique   +7 more
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Contextual factors in systematic reviews: understanding public health interventions in low socioeconomic status and disadvantaged populations

open access: yesArchives of Public Health
Background Evaluations of public health interventions require an understanding of the contextual factors that shape their effectiveness. Context (including socioeconomic, cultural, and environmental factors) plays a critical role in establishing how ...
Mark Rodgers   +4 more
doaj   +1 more source

The delivery of chemotherapy at home: an evidence synthesis

open access: yesHealth Services and Delivery Research, 2015
Background: Recent policy and guidance has focused on chemotherapy services being offered closer to home, but the clinical and economic implications of this are uncertain.
Mark Corbett   +9 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

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