Results 1 to 10 of about 889,487 (200)

Fibroblast growth factor promotes survival of dissociated hippocampal neurons and enhances neurite extension. [PDF]

Proceedings of the National Academy of Sciences, 1986
Basic fibroblast growth factor (FGF) has been found to increase neuronal survival and neurite extension in a highly purified population of fetal rat hippocampal neurons under well-defined serum-free cell culture conditions. In the presence of FGF, neuronal survival after 7 days in culture on a simple plastic substrate is increased 4-fold, to 54% of the
P. Walicke, W. Cowan, N. Ueno, A. Baird, R. Guillemin   +4 more
semanticscholar   +3 more sources

Pulmonary fibrosis requires cell-autonomous mesenchymal fibroblast growth factor (FGF) signaling [PDF]

Journal of Biological Chemistry, 2017
Idiopathic pulmonary fibrosis (IPF) is characterized by progressive pulmonary scarring, decline in lung function, and often results in death within 3–5 five years after diagnosis.
R. Guzy, Ling Li, Craig Smith, Samuel J. Dorry, H. Koo, Lin Chen, D. Ornitz   +6 more
semanticscholar   +3 more sources

The influence of non-neuronal cells on catecholamine and acetylcholine synthesis and accumulation in cultures of dissociated sympathetic neurons. [PDF]

Proceedings of the National Academy of Sciences of the United States of America, 1974
The effects of several non-neuronal cell types on neurotransmitter synthesis in cultures of dissociated sympathetic neurons from the new-born rat were studied.
P. Patterson, L. Chun
semanticscholar   +3 more sources

A dynamically phase-adaptive regulating hydrogel promotes ultrafast anti-fibrotic wound healing

Nature Communications
Achieving rapid and scar-free wound repair is a key goal in the field of regenerative medicine. Herein, a dynamically Schiff base-crosslinked hydrogel (F/R gel) with phase-adaptive regulating functions is constructed to integratedly promote rapid re ...
Fan Zhang, Haijuan Zhang, Shengfu Wang, Mingying Gao, Kaiyi Du, Xinyuan Chen, Yang Lu, Qianqian Hu, Anyu Du, Shenghu Du, Jian Wang, Keqing Shi, Zimiao Chen, Zhuo Li, Zhenglin Li, Jian Xiao   +15 more
doaj   +2 more sources

Synovial tissue from sites of joint pain in knee osteoarthritis patients exhibits a differential phenotype with distinct fibroblast subsets

EBioMedicine, 2021
Background: Synovial inflammation is associated with pain severity in patients with knee osteoarthritis (OA). The aim here was to determine in a population with knee OA, whether synovial tissue from areas associated with pain exhibited different synovial
Dominika E Nanus, Amel Badoume, Susanne N Wijesinghe, Andrea M Halsey, Patrick Hurley, Zubair Ahmed, Rajesh Botchu, Edward T Davis, Mark A Lindsay, Simon W Jones   +9 more
doaj   +1 more source

Enteric Neurospheres Are Not Specific to Neural Crest Cultures: Implications for Neural Stem Cell Therapies [PDF]

, 2015
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work ...
A Barlow, A Pini Prato, A Zani, AG Baynash, AG Catto-Smith, AJ Burns, AJ Burns, Alan J. Burns, AS Wallace, C Caldwell, C Kalcheim, C Laranjeira, CH Knowles, Conor McCann, D Natarajan, Dipa Natarajan, DM Rodrigues, E Panza, Ellen Binder, GE Boeckxstaens, H Tsuji, HM Pallari, J Amiel, Jean-Marie Delalande, Julie Cooper, L Becker, L Ludman, M Hanani, M Metzger, Mara Cananzi, MC Nunes, MD Gershon, Mirella Dottori, MP Sanchez, MT Liu, N Bondurand, N Nagoshi, N Thapar, Nikhil Thapar, NR Druckenbrod, PS Danielian, R Hotta, R Hotta, R Zufferey, Rania Kronfli, RC Mifflin, RM Lindley, S Almond, S Bixby, S Hetz, S Srinivas, S Theocharatos, SJ Conway, SJ Howe, SJ McKeown, TA Heanue, TP Rothman, U Rauch, V Sasselli, X Jiang, Y Matsuda, YH Tsai   +61 more
core   +13 more sources

Generation and characterization of multipotent stem cells from established dermal cultures. [PDF]

PLoS ONE, 2012
Human multipotent skin derived precursor cells (SKPs) are traditionally sourced from dissociated dermal tissues; therefore, donor availability may become limiting.
Rebecca P Hill, Karl Gledhill, Aaron Gardner, Claire A Higgins, Heather Crawford, Clifford Lawrence, Christopher J Hutchison, William A Owens, Bo Kara, S Elizabeth James, Colin A B Jahoda   +10 more
doaj   +1 more source

Internalized PCSK9 dissociates from recycling LDL receptors in PCSK9-resistant SV-589 fibroblasts [PDF]

Journal of Lipid Research, 2014
Secreted PCSK9 binds to cell surface LDL receptor (LDLR) and directs the receptor for lysosomal degradation. PCSK9 is potent at inducing LDLR degradation in cultured liver-derived cells, but it is considerably less active in immortalized fibroblasts. We examined PCSK9 trafficking in SV-589 human skin fibroblasts incubated with purified recombinant wild-
My-Anh Nguyen, Tanja Kosenko, Thomas A. Lagace   +2 more
openaire   +3 more sources

A BMP-FGF morphogen toggle switch drives the ultrasensitive expression of multiple genes in the developing forebrain. [PDF]

PLoS Computational Biology, 2014
Borders are important as they demarcate developing tissue into distinct functional units. A key challenge is the discovery of mechanisms that can convert morphogen gradients into tissue borders.
Shyam Srinivasan, Jia Sheng Hu, D Spencer Currle, Ernest S Fung, Wayne B Hayes, Arthur D Lander, Edwin S Monuki   +6 more
doaj   +1 more source

Establishment and characterization of a primary cell culture derived from external auditory canal squamous cell carcinoma

FEBS Open Bio, 2021
There are no human cancer cell lines of external auditory canal origin available for research use. This report describes the establishment of a culture condition for external auditory canal squamous cell carcinoma, derived from human tumor tissue ...
Yuki Sekino, Akira Imaizumi, Noritaka Komune, Mayumi Ono, Kuniaki Sato, Shogo Masuda, Akiko Fujimura, Kensuke Koike, Takahiro Hongo, Ryutaro Uchi, Hideya Onishi, Takashi Nakagawa   +11 more
doaj   +1 more source