Results 241 to 250 of about 889,606 (319)

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

Advanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao, Yiming Ma, Baihao Shao, Molly M. Stevens   +3 more
wiley   +1 more source

Role of the protease-activated receptor 2 in multi-walled carbon nanotube-induced macrophage polarization <i>ex vivo</i> and airway fibrosis in murine allergic lung disease <i>in vivo</i>. [PDF]

Front Toxicol
Tisch LJ, Bartone RD, Antoniak S, Bonner JC.   +3 more
europepmc   +1 more source

A Conformal Wearable Ultrasound Bioelectronics for Mechanotherapy Reprogramming of Fibroblast Plasticity via Wnt‐FGF10 Axis to Overcome Fibrotic Healing in Urethral Regeneration

Advanced Science, EarlyView.
Fibrotic scarring persistently challenges urethral reconstruction. This study introduces a conformal, wearable ultrasound bioelectronic system that overcomes this by reprogramming fibroblast fate. The device activates a developmental Wnt–FGF10 axis, driving fibroblasts toward a regenerative FGF10+ phenotype that promotes angiogenesis and matrix ...
Mingming Yu, Xingxuan Zhang, Huan Zhang, Jun Wang, Fang Chen, Xiaojun Cai, Yichen Huang, Yuanyi Zheng   +7 more
wiley   +1 more source

Single-cell RNA sequencing clarifies dermal fibroblast subset representation in vitro and reveals variable persistence of keloid disease-associated features

Lock A, Drudi EM, Freydina D, Stramer BM, Denk F, Shaw TJ.   +5 more
europepmc   +1 more source

Reactivation of Human X-Linked Gene and Stable X-Chromosome Inactivation Observed in Generation and Differentiation of iPSCs from a Female Patient with HNRNPH2 Mutation. [PDF]

Cells
Chen G, Rodriguez-Lopez A, Wangsa D, Lomash RM, Huang X, Chen CZ, Bowling RA, Ghousifam N, Banks CJ, Hurd KA, Zou J, Zheng W.   +11 more
europepmc   +1 more source

Nanozymes for Liver Disease Therapy: Advances in Catalytic Activity, Targeting Strategies, and Clinical Translation

Advanced Science, EarlyView.
Nanozymes, as enzyme‐mimicking nanomaterials, exhibit unique catalytic properties for the treatment of liver diseases. By regulating redox homeostasis, modulating immune responses, and enabling targeted delivery, nanozymes overcome the limitations of natural enzymes.
Xiandi Meng, Ge Zhu, Siyu Sun, Wenbo Yao, Yuning Zhang, Yong‐Guang Yang, Tianmeng Sun   +6 more
wiley   +1 more source

Type 2 lymphocytes restrict type 3 lymphocytes during liver fibrosis and colocalize in fibroblast niches. [PDF]

Sci Adv
Sbierski-Kind J, Cautivo KM, Nilsson J, Wagner JC, Dahlgren MW, Crystal NE, McClave M, Mroz NM, Ganslmeier M, Lizama CO, Gan AL, Matatia PR, Taruselli MT, Chang AA, Caryotakis S, O'Leary CE, Kotas M, Lee JH, Gu T, Seo H, Kim HJ, Mattis AN, Peng T, Locksley RM, Molofsky AB.   +24 more
europepmc   +1 more source

Pathogenic Keratinocyte States and Fibroblast Niches Define the Tissue Microenvironment in Severe Hidradenitis Suppurativa

Du-Harpur X, Ganier C, Mazin P, Cheshire C, Rashidghamat E, Luscombe NM, Lynch MD, Watt FM.   +7 more
europepmc   +1 more source

Mesenchymal and neural stem cell differentiation into Purkinje-like cells: Morphological study. [PDF]

J Taibah Univ Med Sci
Mohammad MH, Al-Shammari AM, Aljuboori AA, Hussamildeen R, Al-Hilli ZA.   +4 more
europepmc   +1 more source