Results 61 to 70 of about 889,606 (319)

Differences in glycosaminoglycans synthesized by fibroblast-like cells from chick cornea, heart, and skin.

Journal of Biological Chemistry, 1977
Glycosaminoglycan biosynthesis was studied in primary cultures in vitro to determine if fibroblast-like cells from different individual tissues synthesize the same or different patterns of glycosaminoglycans.
G. Conrad, C. Hamilton, E. Haynes
semanticscholar   +1 more source

Pigmented melanoma cell migration study on murine syngeneic B16F10 melanoma cells or tissue transplantation models [PDF]

, 2019
Melanoma is a lethal form of skin cancer with poor prognosis, especially due to the early metastatic feature. Recent studies have shown that the melanin pigment influences the nanomechanical properties and, therefore, the metastatic behavior of the ...
Buteică, Sandra Alice, Mîndrilă, Bogdan, Mîndrilă, Ion, Mărginean, Ovidiu Marcel, Niculescu, Mihaela, Predoi, Maria-Cristina   +5 more
core   +2 more sources

A human lung tumor microenvironment interactome identifies clinically relevant cell-type cross-talk. [PDF]

, 2020
BackgroundTumors comprise a complex microenvironment of interacting malignant and stromal cell types. Much of our understanding of the tumor microenvironment comes from in vitro studies isolating the interactions between malignant cells and a single ...
Azizi, Armon, Bejnood, Alborz, Bouchard, Gina, Diehn, Maximilian, Feng, Weiguo, Forgó, Erna, Gentles, Andrew J, Hoang, Chuong D, Hui, Angela Bik-Yu, Jeong, Youngtae, Knowles, David A, Kuong, Amanda, Nair, Ramesh V, Nair, Viswam S, Plevritis, Sylvia K, van de Rijn, Matt, Varma, Sushama, West, Rob, Xu, Yue, Yu, Alice   +19 more
core   +4 more sources

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

Morphological Differentiation of Astroglial Progenitor Cells from Egf-Responsive Neurospheres in Response to Fetal Calf Serum, Basic Fibroblast Growth Factor, and Retinol

Cell Transplantation, 1996
Procurement of multipotential neuroglial stem cells is possible with the addition of epidermal growth factor (EGF). Stem cells will differentiate into neurons and glia upon the removal of EGF from the culture medium.
Yung H. Chiang, Vincenzo Silani, Feng C. Zhou   +2 more
doaj   +1 more source

Protein kinase C regulates human pluripotent stem cell self-renewal.

PLoS ONE, 2013
BackgroundThe self-renewal of human pluripotent stem (hPS) cells including embryonic stem and induced pluripotent stem cells have been reported to be supported by various signal pathways.
Masaki Kinehara, Suguru Kawamura, Daiki Tateyama, Mika Suga, Hiroko Matsumura, Sumiyo Mimura, Noriko Hirayama, Mitsuhi Hirata, Kozue Uchio-Yamada, Arihiro Kohara, Kana Yanagihara, Miho K Furue   +11 more
doaj   +1 more source

Characterisation of feline renal cortical fibroblast cultures and their transcriptional response to transforming growth factor beta 1 [PDF]

, 2018
Chronic kidney disease (CKD) is common in geriatric cats, and the most prevalent pathology is chronic tubulointerstitial inflammation and fibrosis. The cell type predominantly responsible for the production of extra-cellular matrix in renal fibrosis is ...
A Clayton, A Desmouliere, A Holmes, A Yabuki, AA Eddy, AA Eddy, AC Sanchez-Lara, BL Aken, C Grupp, C. P. D. Wheeler-Jones, CH Heldin, CL Marino, E Honda, E Van Obberghen-Schilling, F Strutz, F Strutz, F Syeda, GR Grotendorst, H. M. Syme, HP Rodemann, J Ivaska, J Lu, J. Elliott, J. S. Lawson, JL Mumaw, JS Lawson, K Sawashima, KG McCullagh, KJ Kelynack, LC Penning, M Prunotto, M Zeisberg, MA Venkatachalam, MJ Ryan, MK Phanish, ML Sequeira Lopez, P Boor, P Sysa, PC Bartlett, Q Chai, RA Ignotz, S Chakrabarti, S Meran, S Moll, S Neelisetty, SC Chen, SL Lin, SP DiBartola, SW Smith, T Akamatsu, TA Wynn, V Dugina, VS Lebleu, W Bloom, WA Border, X Pan, XM Meng, Y Hosokawa, Y Liu   +58 more
core   +2 more sources

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

FGF6 and FGF9 regulate UCP1 expression independent of brown adipogenesis

Nature Communications, 2020
Uncoupling protein-1 (UCP1) plays a central role in energy dissipation in brown adipose tissue (BAT). Using high-throughput library screening of secreted peptides, we identify two fibroblast growth factors (FGF), FGF6 and FGF9, as potent inducers of UCP1
F. Shamsi, R. Xue, Tian Lian Huang, M. Lundh, Yang Liu, L. O. Leiria, M. Lynes, Elena Kempf, Chih-Hao Wang, Satoru Sugimoto, P. Nigro, Kathrin Landgraf, T. Schulz, Yiming Li, B. Emanuelli, S. Kothakota, L. Williams, N. Jessen, S. Pedersen, Y. Böttcher, M. Blüher, A. Körner, L. Goodyear, M. Mohammadi, C. Kahn, Y. Tseng   +25 more
semanticscholar   +1 more source

Distinct molecular interactions mediate neuronal process outgrowth on non-neuronal cell surfaces and extracellular matrices. [PDF]

, 1986
We have compared neurite outgrowth on extracellular matrix (ECM) constituents to outgrowth on glial and muscle cell surfaces. Embryonic chick ciliary ganglion (CG) neurons regenerate neurites rapidly on surfaces coated with laminin (LN), fibronectin (FN),
Bixby, JL, Reichardt, LF, Tomaselli, KJ
core   +1 more source