Results 81 to 90 of about 390,003 (343)

The Impact of Roaming Radicals on the Combustion Properties of Transportation Fuels

, 2017
A systematic investigation on the effects of roaming radical reactions on global combustion properties for transportation fuels is presented. New software was developed that can automatically discover all the possible roaming pathways within a given ...
Goldsmith, C. Franklin, West, Richard H.
core   +1 more source

The solvation and dissociation of 4-benzylaniline hydrochloride in chlorobenzene [PDF]

, 2014
A reaction scheme is proposed to account for the liberation of 4-benzylaniline from 4-benzylaniline hydrochloride, using chlorobenzene as a solvent at a temperature of 373 K.
Alice A. Miller, Amrute A. P., Archie Eaglesham, Badawi H., Ball D. W., Brock F. H., Burkus J., Cavani F., David Adam, David Lennon, Di Giacomo A., Ding J., Dunlap K. L., Emma K. Gibson, Fogg P. G. T., Freeman R., Frost A. A., Gibson E. K., Gibson E. K., Guéron M., Hevia M. A. G., John M. Winfield, Khairuzzaman A., López N., Mitchell C. J., Mondelli C., Over H., Randall D., Richter R. H., Robert H. Carr, Serajuddin A. T. M., Silkov A. A., Sun S., Sutherland I. W., Tebutt P., Ulrich H., Ulrich H., Yang P. F., Zhang T., Zhang T., Zhang T.   +40 more
core   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

De Svante Arrhenius ao peagâmetro digital: 100 anos de medida de acidez From Svante Arrhenius to the digital ph meter: a century of acidity measurement

Química Nova, 2007
This work describes the establishment of the concept of pH and the evolution of its measurement. The origin of the pH definition can be found in the development of the chemistry of aqueous solutions during the XIXth century. The electrolytic dissociation
Michelle da Silva Gama, Júlio Carlos Afonso   +1 more
doaj   +1 more source

On the Energy-specific Photodissociation Pathways of 14N2 and 14N15N Isotopomers to N Atoms of Different Reactivity: A Quantum Dynamical Perspective

The Astrophysical Journal, 2023
Photodissociation of the nitrogen molecule in the vacuum ultraviolet (VUV) is a major source of reactive nitrogen atoms in the upper atmosphere of Earth and throughout the solar system.
Natalia Gelfand, Ksenia Komarova, Francoise Remacle, Raphael D. Levine   +3 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Sensing Microorganisms Using Rapid Detection Methods: Supramolecular Approaches

Biosensors
Supramolecular chemistry relies on the dynamic association/dissociation of molecules through non-covalent interactions. These interactions of a self-assembled system can be strategically exploited for sensing several microorganisms.
Hiya Lahiri, Kingshuk Basu
doaj   +1 more source

Hydroxylation Structure and Proton Transfer Reactivity at the Zinc Oxide-Water Interface [PDF]

, 2011
The hydroxylation structural features of the first adsorption layer and its connection to proton transfer reactivity have been studied for the ZnO-liquid water interface at room temperature. Molecular dynamics simulations employing the ReaxFF forcefield
Goddard, William A., III, Hermansson, Kersti, Raymand, David, Spångberg, Daniel, van Duin, Adri C. T.   +4 more
core  

Evolution of PAHs in photodissociation regions: Hydrogenation and charge states

, 2013
Various studies have emphasized variations of the charge state and composition of the interstellar polycyclic aromatic hydrocarbon (PAH) population in photodissociation regions (PDRs). We aim to model the spatial evolution of the charge and hydrogenation
Joblin, C., Montillaud, J., Toublanc, D.
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source