Results 31 to 40 of about 936,316 (178)

Albendazole Solid Dispersions: Influence of Dissolution Medium Composition on In Vitro Drug Release [PDF]

, 2014
The rate-limiting step to drug absorption is often dissolution from the dosage form, especially for poorly soluble com-pounds. Two possibilities for improving the dissolution of these drugs are to increase the available surface area and to im-prove their
Allemandi, Daniel Alberto, Castro, Silvina Gabriela, González Vidal, Noelia Luján, Palma, Santiago Daniel, Sanchez Bruni, Sergio Fabian   +4 more
core   +1 more source

A Fundamental Paradigm for Coral Reef Carbonate Sediment Dissolution

Frontiers in Marine Science, 2015
The long-term success of coral reefs depends on a positive balance of calcium carbonate production exceeding dissolution, erosion, and material export.
Andreas J Andersson
doaj   +1 more source

Studying the Impact of the Temperature and Sorbed Water during Microwave-Induced In Situ Amorphization: A Case Study of Celecoxib and Polyvinylpyrrolidone

Pharmaceutics, 2021
Microwave-induced in situ amorphization of a drug into a polymeric amorphous solid dispersion (ASD) has been suggested to follow a dissolution process of the drug into the polymeric network, at temperatures above the glass transition temperature (Tg) of ...
Nele-Johanna Hempel, Matthias M. Knopp, Korbinian Löbmann, Ragna Berthelsen   +3 more
doaj   +1 more source

A Potassium Based Fluorine Containing Bioactive Glass for Use as a Desensitizing Toothpaste

Molecules, 2021
Potassium releasing bioactive glasses (BAGs) may offer improved relief for dentine hypersensitivity compared to conventional sodium containing BAGs by releasing K+ ions for nerve desensitization and occluding dentinal tubules to prevent fluid flow within
Melissa Tiskaya, David Gillam, Saroash Shahid, Robert Hill   +3 more
doaj   +1 more source

Comprehensive Dissolution Study on Two Double Ce(IV) Phosphates with Evidence of Secondary CeO₂ Nanoparticle Formation

Molecules
Herein, we present a comprehensive study on the dissolution behaviour of two sodium–cerium(IV) phosphate phases synthesised hydrothermally from CeO2 nanoparticles: crystalline Na2Ce(PO4)2 and nanocrystalline NaCe2(PO4)3.
Anastasiia L. Listova, Anastasiia S. Kuzenkova, Mikhail A. Gerasimov, Elizaveta S. Kulikova, Roman D. Svetogorov, Daniil A. Novichkov, Alexei A. Averin, Vasiliy O. Yapaskurt, Anna Yu. Romanchuk, Stepan N. Kalmykov, Tatiana V. Plakhova   +10 more
doaj   +1 more source

The Pandemic Wave’s Legal Effects on Entrepreneurship in Romania. A Compilation from Midway Through the Global Health Crisis (I)

CECCAR Business Review
The rapidly developing coronavirus pandemic’s footprint requires a deeper investigation in terms of the consequences on the business environment. The literature on this subject is vast, as confirmed by the present work, the unprecedented health situation
Claudia-Florina BOTAR
doaj   +1 more source

Biopharmaceutics of Topical Ophthalmic Suspensions: Importance of Viscosity and Particle Size in Ocular Absorption of Indomethacin

Pharmaceutics, 2021
Eye drops of poorly soluble drugs are frequently formulated as suspensions. Bioavailability of suspended drug depends on the retention and dissolution of drug particles in the tear fluid, but these factors are still poorly understood.
Elisa Toropainen, Sara J. Fraser-Miller, Dunja Novakovic, Eva M. Del Amo, Kati-Sisko Vellonen, Marika Ruponen, Tapani Viitala, Ossi Korhonen, Seppo Auriola, Laura Hellinen, Mika Reinisalo, Unni Tengvall, Stephanie Choi, Mohammad Absar, Clare Strachan, Arto Urtti   +15 more
doaj   +1 more source

MOCCA Survey Database I: Dissolution of tidally filling star clusters harbouring BH subsystems

, 2019
We investigate the dissolution process for dynamically evolving star clusters embedded in an external tidal field by exploring the MOCCA Survey Database I, with focus on the presence and evolution of a stellar-mass black hole subsystem. We argue that the
Askar, Abbas, Giersz, Mirek, Hypki, Arkadiusz, Leveque, Agostino, Spurzem, Rainer, Wang, Long   +5 more
core   +2 more sources

The Amorphous Solid Dispersion of Chrysin in Plasdone^® S630 Demonstrates Improved Oral Bioavailability and Antihyperlipidemic Performance in Rats

Pharmaceutics, 2023
Chrysin is a flavonoid with various biological activities. However, its low water solubility and strong metabolism render its oral bioavailability rather poor.
Chenhui Wang, Xiaowei Liu, Ruihan Zhao, Meiqing Yang, Wenqian Liu, Qiuyang Dai, Xiaofeng Bao, Yong Chen, Jun Ma   +8 more
doaj   +1 more source

High-Payload Nanosuspension of Centella asiatica Extract for Improved Skin Delivery with No Irritation

International Journal of Nanomedicine, 2021
Eun A Kim, Jun Soo Park, Min Seop Kim, Min Young Jeong, Hyun Jin Park, Jun Hyuk Choi, Jae Hee Seo, Yong Seok Choi, Myung Joo Kang College of Pharmacy, Dankook University, Cheonan, Chungnam, 330-714, KoreaCorrespondence: Myung Joo KangCollege of Pharmacy,
Kim EA, Park JS, Kim MS, Jeong MY, Park HJ, Choi JH, Seo JH, Choi YS, Kang MJ   +8 more
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