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MCM-41 for furosemide dissolution improvement
Microporous and Mesoporous Materials, 2012Abstract The ordered mesoporous silica material MCM-41 was used to prepare a novel drug delivery system (DDS) for oral administration of the diuretic furosemide (FURO), labeled in class IV of the Biopharmaceutics Classification System (BCS). This drug is characterized by both low solubility and permeability and its absorption window is the stomach ...
AMBROGI, Valeria +6 more
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An Improved Method for Dissolution of Uranium Tetrafluoride.
Analytical Chemistry, 1962Dissolution of UF/sub 4 in a mixture of (NH/sub 4/)/sub 2/ SO/sub 4/ and H/s ub 2/SO/sub 4/ and boric acid is described. For large-sized samples, addition of boric acid appreciably hastened dissolution, and a 15-gram sample was dissolved in 30 min in quartz glassware. The cooled melt is soluble in distilled water. (M.C.G.)
W. M. Wise +2 more
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Ternary solid dispersion to improve solubility and dissolution of meloxicam
Journal of Basic and Clinical Physiology and Pharmacology, 2019Abstract Background Meloxicam (MLX) is a potent non-steroidal anti-inflammatory drug with poor solubility. Solid dispersion (SD) is an effective formulation strategy to improve the dissolution rate of poorly water-soluble compounds.
Dwi, Setyawan +2 more
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Improvement of the wettability and dissolution of fenofibrate compacts by plasma treatment
International Journal of Pharmaceutics, 2011The goal of this study was to investigate the effect of plasma treatment on the wettability and dissolution of fenofibrate compacts. Contact angle measurements and intrinsic dissolution rate studies of untreated and plasma-treated fenofibrate compacts were conducted.
Philipp, Buch +2 more
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Improving cystine stone therapy: an in vitro study of dissolution
Urology, 2000To perform an in vitro study analyzing the possibilities in therapeutic strategies for an effective treatment of cystine stones.Artificial stones made of cystine [Bon(n)-Stones] with a ball-shaped size of 0.9 cm in diameter were used. Chemolysis of artificial cystine stones with different solvents (artificial urine, physiologic sodium chloride solution,
D, Heimbach +3 more
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Improvement of Dissolution Properties of Furosemide by Complexation with β-Cyclodextrin
Drug Development and Industrial Pharmacy, 1998The purpose of this study was to increase the solubility of furosemide (FR) with inclusion compound of beta-cyclodextrin (beta-CD). The interaction between FR and beta-CD in solution was studied by the solubility method. The phase solubility studies reveal a Bs-type diagram with an inclusion complex of 1:1 molar ratio and a stability constant of 823.5 ...
N, Ozdemir, S, Ordu
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Improvement in the dissolution properties of theophylline with ß-cyclodextrin
1994An improvement in the dissolution of theophylline with beta-cyclodextrin was achieved by subjecting them to co-grinding and freeze-drying methods. The products obtained were examined by the phase solubility method, differential scanning calorimetry and X-ray diffractometry.
YAZAN, Y, SUMNU, M
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Improvement of clofibrate dissolution by complexation with cyclodextrin
International Journal of Pharmaceutics, 1996Abstract Inclusion complexes of clofibrate with β-cyclodextrin (βCD) were prepared by coprecipitation, kneading and sealed heating methods and characterized by UV spectrophotometry, differential scanning calorimetry, X-ray diffractometry and infrared spectroscopy. All results were in keeping with the formation of 1:1 inclusion complex.
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Co-precipitates of lumefantrine-Eudragit E PO for dissolution improvement
Annales Pharmaceutiques Francaises, 2022Sarika Wairkar
exaly