Impact of Tablet Shape on Drug Dissolution Rate Through Immediate Released Tablets [PDF]
Purpose: The aim of this study was to evaluate the influence of the geometric shape on the dissolution rate of the domperidone, a drug model for immediate release dosage form.
Fatima Molavi +2 more
doaj +3 more sources
Microneedles with Tunable Dissolution Rate.
Dissolvable microneedle (MN) patches have been widely investigated for transdermal drug delivery. The dissolution rate of MN controls the status of drug release from the MN, which in turn determines drug absorption through skin.
Himanshu Kathuria +4 more
semanticscholar +3 more sources
Intrinsic Dissolution Modeling: Interdependence Between Dissolution Rate, Solubility, and Boundary Layer Thickness [PDF]
Background/Objectives: In the past, many drug release models have been presented which attempt to describe the interaction of drugs and excipients in a formulation.
Amelie Marie Mattusch +3 more
doaj +2 more sources
Enhancement of ketoconazole dissolution rate by the liquisolid technique
The study was conducted to enhance the dissolution rate of ketoconazole (KCZ) (a poorly water-soluble drug) using the liquisolid technique. Microcrystalline cellulose, colloidal silica, PEG400 and polyvinyl pyrrolidone (PVP) were employed as a carrier ...
Molaei Mir-Ali +5 more
doaj +2 more sources
The Alkaline Dissolution Rate of Calcite. [PDF]
Due to the widespread presence of calcium carbonate on Earth, several geochemical systems, among which is the global CO2 cycle, are controlled to a large extent by the dissolution and precipitation of this mineral. For this reason, the dissolution of calcite has been thoroughly investigated for decades. Despite this intense activity, a consensual value
J. Colombani
semanticscholar +3 more sources
The dissolution study of a South African magnesium-based material from different sources using a pH-stat [PDF]
One of the main steps in the wet flue gas desulphurization (WFGD) process is the dissolution of either magnesite or limestone. Evaluating the magnesite dissolution rate is vital for the design and efficient operation of wet FGD plants.
Limo Rutto Hilary +1 more
doaj +3 more sources
Intrinsic Dissolution Rate Profiling of Poorly Water-Soluble Compounds in Biorelevant Dissolution Media [PDF]
The intrinsic dissolution rate (IDR) of active pharmaceutical ingredients (API) is a key property that aids in early drug development, especially selecting formulation strategies to improve dissolution and thereby drug absorption in the intestine.
Alexandra Teleki +2 more
doaj +2 more sources
A New Challenge for the Old Excipient Calcium Carbonate: To Improve the Dissolution Rate of Poorly Soluble Drugs [PDF]
Calcium carbonate is an excipient traditionally used in solid dosage forms with several functions such as a diluent, a quick dissolution agent, a buffer and an opacifier.
Valeria Ambrogi
doaj +2 more sources
Dissolution Rate of Various Limes into Steelmaking Slag
In the steelmaking process, various solid oxides such as lime and dolomite are used as flux. It is well known that the dissolution rate of these oxides into the molten slag has an important role to increase the reaction rate between the steel and slag ...
Maruoka Nobuhiro +3 more
doaj +2 more sources
Investigation of the Storage and Stability as Well as the Dissolution Rate of Novel Ilaprazole/Xylitol Cocrystal [PDF]
Reflux esophagitis, a treatment for gastric ulcers known as Ilaprazole (Ila), is not stable during storage and handling at room temperature, requiring storage at 5 degrees Celsius. In this study, to address these issues with Ila, coformers rich in oxygen
Sihyun Nam +6 more
doaj +2 more sources

