Intrinsic Dissolution Rate Profiling of Poorly Water-Soluble Compounds in Biorelevant Dissolution Media [PDF]
Pharmaceutics, 2020 The intrinsic dissolution rate (IDR) of active pharmaceutical ingredients (API) is a key property that aids in early drug development, especially selecting formulation strategies to improve dissolution and thereby drug absorption in the intestine.
Alexandra Teleki +2 more
doaj +2 more sources
Intrinsic Dissolution Modeling: Interdependence Between Dissolution Rate, Solubility, and Boundary Layer Thickness [PDF]
PharmaceuticsBackground/Objectives: In the past, many drug release models have been presented which attempt to describe the interaction of drugs and excipients in a formulation.
Amelie Marie Mattusch +3 more
doaj +2 more sources
Study of the impact of different salts on the intrinsic dissolution rate of pharmaceutical compounds [PDF]
, 2017 The intrinsic dissolution rate (IDR) of a free base and its four salts were investigated with the aim of selecting the salt with the best dissolution performance.
Box, Karl +3 more
core +2 more sources
The dissolution study of a South African magnesium-based material from different sources using a pH-stat [PDF]
Chemical Industry and Chemical Engineering Quarterly, 2011 One of the main steps in the wet flue gas desulphurization (WFGD) process is the dissolution of either magnesite or limestone. Evaluating the magnesite dissolution rate is vital for the design and efficient operation of wet FGD plants.
Limo Rutto Hilary +1 more
doaj +3 more sources
Investigation of the Storage and Stability as Well as the Dissolution Rate of Novel Ilaprazole/Xylitol Cocrystal [PDF]
PharmaceuticsReflux esophagitis, a treatment for gastric ulcers known as Ilaprazole (Ila), is not stable during storage and handling at room temperature, requiring storage at 5 degrees Celsius. In this study, to address these issues with Ila, coformers rich in oxygen
Sihyun Nam +6 more
doaj +2 more sources
Impact of Tablet Shape on Drug Dissolution Rate Through Immediate Released Tablets [PDF]
Advanced Pharmaceutical Bulletin, 2020 Purpose: The aim of this study was to evaluate the influence of the geometric shape on the dissolution rate of the domperidone, a drug model for immediate release dosage form.
Fatima Molavi +2 more
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Yoghurt as a deglutition aid for oral medication: effects on famotidine powder dissolution rate and pharmacokinetics. [PDF]
Sci Rep, 2023 Gotoh Y +5 more
europepmc +3 more sources
Zhongguo dizhi zaihai yu fangzhi xuebao, 2021 The Liaoshan tunnel is one of the controlling projects of the E-han expressway, the karst geological conditions in the tunnel site area are complex. In order to deeply study the characteristics of carbonate dissolution in the field, this paper takes the ...
Huaming LI +4 more
doaj +1 more source
Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2023 Cocrystallization is an emerging approach for improving physico-chemical characteristics of an active pharmaceutical ingredient (API) for instance dissolution rate, solubility, stability in addition to mechanical properties without affecting their ...
Ameera A Radhi +3 more
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Enhance dissolution rate and solubility of solid drugs through pharmaceutical deep eutectic solvents
Zanco Journal of Pure and Applied Sciences, 2021 Pharmaceutical active ingredients are usually sold in the markets in the form of solid drugs. These drugs are often associated with some problems like polymorphism, bioavailability and low solubility.
Idrees Bakr Qader
doaj +1 more source