Results 11 to 20 of about 555,478 (356)

Small-scale dissolution test screening tool to select potentially substandard and falsified (SF) medicines requiring full pharmacopoeial analysis

open access: yesScientific Reports, 2021
The purpose of this study was to design a convenient, small-scale dissolution test for extracting potential substandard and falsified (SF) medicines that require full pharmacopoeial analysis. The probability of metronidazole samples complying with the US
Mohammad Sofiqur Rahman   +5 more
doaj   +1 more source

DEVELOPMENT OF NITROFURAN DERIVATIVE: COMPOSITION AND TECHNOLOGY OF EFFERVESCENT TABLETS WITH SOLID DISPERSIONS

open access: yesФармация и фармакология (Пятигорск), 2022
Taking into account the current Product specification file, the aim of the work was to develop the composition and technology for obtaining effervescent tablets based on solid dispersions of furazolidone in the form of an aqueous solution for external ...
A. O. Elagina   +10 more
doaj   +1 more source

Preparation and characterization of fenofibrate-loaded zeolitic imidazolate frameworks and their evaluation in dissolution enhancement of the formulation [PDF]

open access: yesشیمی کاربردی روز, 2021
The purpose of this study was to develop zeolitic imidazolate frameworks (ZIFs) incorporated with poorly water-soluble drug fenofibrate (FEN), belonging to Biopharmaceutical Classification System (BCS) class II, to improve drug dissolution, intended to ...
Aziz maleki   +5 more
doaj   +1 more source

Preparation and Characterization of Instant Casein Phosphopeptide by Supercritical Fluid Assisted Atomization

open access: yesFoods, 2021
Casein phosphopeptide (CPP) has been widely used as micronutrient supplementation for certain populations. However, its solubility performance is far from satisfying.
Jian Zhu   +5 more
doaj   +1 more source

Investigation of Dissolution Mechanism and Release Kinetics of Poorly Water-Soluble Tadalafil from Amorphous Solid Dispersions Prepared by Various Methods

open access: yesPharmaceutics, 2019
The aims of this study were to investigate how the release of tadalafil is influenced by two grades of polyvinylpyrrolidone (Kollidon® 12 PF and Kollidon® VA 64) and various methods of preparing solid dispersions (solvent evaporation, spray ...
Tereza Školáková   +5 more
doaj   +1 more source

Compositional controls on melting and dissolving a salt into a ternary melt [PDF]

open access: yes, 2007
We explore theoretically the controls on dissolution of salt A, in an undersaturated brine of salts A and B. We show that, as the concentration of B increases, the dissolution rate of A decreases, for brine of given temperature.
Hatton, DC, Woods, AW
core   +2 more sources

Dissolution enhancement of gliclazide using pH change approach in presence of twelve stabilizers with various physico-chemical properties [PDF]

open access: yes, 2009
Purpose. The micronization using milling process to enhance dissolution rate is extremely inefficient due to a high energy input, and disruptions in the crystal lattice which can cause physical or chemical instability.
Mostafavi, Seyed Abolfazl   +3 more
core   +2 more sources

Addition of Sodium Bicarbonate to Irrigation Solution May Assist in Dissolution of Uric Acid Fragments During Ureteroscopy [PDF]

open access: yes, 2018
Introduction: We hypothesized that adding sodium bicarbonate (bicarb) to normal saline (NS) irrigation during ureteroscopy in patients with uric acid (UA) nephrolithiasis may assist in dissolving small stone fragments produced during laser lithotripsy ...
Lingeman, James E.   +2 more
core   +1 more source

Dissolution dominating calcification process in polar pteropods close to the point of aragonite undersaturation [PDF]

open access: yes, 2014
Thecosome pteropods are abundant upper-ocean zooplankton that build aragonite shells. Ocean acidification results in the lowering of aragonite saturation levels in the surface layers, and several incubation studies have shown that rates of calcification ...
AG Dickson   +57 more
core   +3 more sources

Modification of the Release of Poorly Soluble Sulindac with the APTES-Modified SBA-15 Mesoporous Silica

open access: yesPharmaceutics, 2021
The effectiveness of oral drug administration is related to the solubility of a drug in the gastrointestinal tract and its ability to penetrate the biological membranes. As most new drugs are poorly soluble in water, there is a need to develop novel drug
Adrianna Dadej   +8 more
doaj   +1 more source

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