Results 251 to 260 of about 5,482,491 (310)
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Microneedles with Tunable Dissolution Rate
ACS Biomaterials Science & Engineering, 2020Dissolvable microneedle (MN) patches have been widely investigated for transdermal drug delivery. The dissolution rate of MN controls the status of drug release from the MN, which in turn determines drug absorption through skin. However, no systematic approaches have been reported to tune the dissolution profile of dissolvable MN matrices.
Himanshu Kathuria +4 more
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Dissolution Rate Equations in CoIumn-Confined Dissolution
Journal of Pharmaceutical Sciences, 1976Equations are derived for the dissolution of a soluble solid in a column into a liquid stream. The equations are substantiated by experiments using oxalic acid dihydrate as a test substance. The dissolution rate constant, k, of oxalic acid dihydrate depends on linear velocity, v (centimeters per second), by the following equation: k = (2.54 +/- 0.76) X
J T, Carstensen, K, Dhupar
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Dissolution rates of silicate cements
Biomaterials, 1982The literature relating to the dissolution of the silicate cements is reviewed, including the methodology, intrinsic factors relating to composition and method of mixing, curing etc. and extrinsic factors, i.e. the medium, pH, ionic strength etc. to which the sample of cement is exposed.
A T, Kuhn, G B, Winter, W K, Tan
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Nonsink Dissolution Rate Equations
Journal of Pharmaceutical Sciences, 1975In spite of the fact that film theory is based on severe assumptionss, it is shown to be a good working model. The Niebergall-Goyan equation, the Short-Sharkey-Rhodes equation, and the Pothisiri-Carstensen equation-all based on simple film theory-are shown to hold through 80-90% of the dissolutin process for p-hydroxybenzoic acid and sodium chloride ...
M, Patel, J T, Carstensen
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Dissolution Rates of Polyphase Mixtures
Journal of Pharmaceutical Sciences, 1965The theory for the dissolution rate of polyphase mixtures has been investigated and applied to several situations. Physical models involving simultaneous diffusion and rapid equilibria have led to relationships that describe experimental data rather well for the benzoic acid–salicylic acid, the benzocaine–caffeine, and the benzoic acid–trisodium ...
W I, Higuchi, N A, Mir, S J, Desai
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Nonsink Dissolution Rate Equation
Journal of Pharmaceutical Sciences, 1973An equation was developed which describes the dissolution of monodisperse particles beyond the point where concentrations are small compared to solubility. If it is assumed that a stagnant layer model applies, the thickness of these layers is of the same order of magnitude as calculated via the Hixson-Crowell treatment but dissolution rate constants ...
P, Pothisiri, J T, Carstensen
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Controlled Release with Finite Dissolution Rate
SIAM Journal on Applied Mathematics, 2011We consider a two-phase generalization of the classical Higuchi model for controlled drug release. The drug is assumed to be prepared in a stent in its solid phase by immersion in a polymeric matrix, which eventually delivers the drug when it reaches the free end.
BISCARI, PAOLO +4 more
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Investigation of dissolution kinetics for high rates of dissolution
Soviet Physics Journal, 1970A procedure was developed for investigating the dissolution of crystals that rub against a substrate with the solvent, whereby the process becomes significantly intensified. A theory of the method is presented. The kinetics of dissolution of azobenzene in alcohol at different rates of substrate motion, normal loads on the crystal, and temperatures is ...
N. N. Nilova +2 more
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The dissolution rate of zinc pyrithione
International Journal of Cosmetic Science, 1985SynopsisA method of measuring and correlating the rate at which zinc pyrithione dissolves during a shampoo is described. The rise in zinc concentration of a solution in a stirred vessel following the introduction of a dose of zine pyrithione suspension was measured as a function of time using atomic absorption spectrophotometry. An analysis of the mass
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THE RATE OF DISSOLUTION OF COPPER
Canadian Journal of Chemistry, 1954The rate of dissolution of polycrystalline metallic copper in sulphuric acid solutions has been determined as a function of temperature, oxygen pressure, rotation speed, hydrogen ion concentration, sample area, and corroding solution volume. A typical set of conditions would involve a volume of 500 ml.
Benjamin C.-Y. Lu, W. F. Graydon
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