Results 271 to 280 of about 11,632,967 (345)

Dissolution Rates of Polyphase Mixtures

Journal of Pharmaceutical Sciences, 1965
The theory for the dissolution rate of polyphase mixtures has been investigated and applied to several situations. Physical models involving simultaneous diffusion and rapid equilibria have led to relationships that describe experimental data rather well for the benzoic acid–salicylic acid, the benzocaine–caffeine, and the benzoic acid–trisodium ...
W I, Higuchi, N A, Mir, S J, Desai
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Dissolution Rates under Sink Conditions

Journal of Pharmaceutical Sciences, 1971
Abstract Equations are given for the dissolution of a drug into an aqueous phase overlayered with a lipid phase, in which back transfer from the lipid phase is assumed possible. Consideration of both the presence and absence of back transfer, assuming in each that the amount of drug in the aqueous phase either approaches saturation or remains ...
P J, Niebergall, E T, Sugita, R L, Schnaare   +2 more
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Chalcopyrite dissolution rate laws

Applied Geochemistry, 2010
Abstract Meta-analysis of 173 rate measurements from 21 publications was used to develop rate laws for chalcopyrite dissolution under environmentally relevant conditions. Multiple linear regression analysis of 28 data for nonoxidative chalcopyrite dissolution in the presence of O2 and Cl− produced the following rate law: r = 10 - 1.52
Bryn E. Kimball, J. Donald Rimstidt, Susan L. Brantley   +2 more
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Solid Dispersion Approach Improving Dissolution Rate of Stiripentol: a Novel Antiepileptic Drug

Iranian journal of pharmaceutical research, 2015
Some drugs have low bioavailability due to their poor aqueous solubility and/or slow dissolution rate in biological fluids. Stiripentol (STP) is a novel anticonvulsant drug that is structurally unrelated to the currently available antiepileptics.
S. Afifi
semanticscholar   +1 more source

Controlled Release with Finite Dissolution Rate

SIAM Journal on Applied Mathematics, 2011
We consider a two-phase generalization of the classical Higuchi model for controlled drug release. The drug is assumed to be prepared in a stent in its solid phase by immersion in a polymeric matrix, which eventually delivers the drug when it reaches the free end.
BISCARI, PAOLO, S. Minisini, PIEROTTI, DARIO GIANCARLO, VERZINI, GIANMARIA, ZUNINO, PAOLO   +4 more
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Dissolution Rates of Pure Nonionic Surfactants

Langmuir, 2000
no ...
Chen, B. H., Miller, C. A., Walsh, J. M., Warren, P. B., Ruddock, J. N., Garrett, P. R., Argoul, Françoise, Léger, Christophe   +7 more
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Precision Apparatus for Dissolution Rate Determinations

Journal of Pharmaceutical Sciences, 1964
An apparatus particularly useful for intrinsic dissolution rate determinations by the rotating disk method is described. It affords precision speed control, wide range of rotation rates, good shaft concentricity, and maintains constant speed over extended periods of time.
G, LEVY, W, TANSKI
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Variability of Zinc Oxide Dissolution Rates

Environmental Science & Technology, 2017
Zinc oxide (ZnO) is of widespread use for numerous applications, including many in the cosmetic industry. Thus, ZnO particles are quite likely to enter the environment. ZnO may be harmful because of the release of cytotoxic Zn2+ ions during dissolution reactions.
Monika Michaelis, Cornelius Fischer, Lucio Colombi Ciacchi, Andreas Luttge   +3 more
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Dissolution Modeling: Factors Affecting the Dissolution Rates of Polydisperse Powders

Pharmaceutical Research, 1993
The dissolution rates of two lots of hydrocortisone (fine and coarse) were simulated using a computer program based on a Noyes-Whitney-type equation. Derivations of the equation were made to compare the accuracy of simulations using spherical and cylindrical particle geometry, with and without a time-dependent diffusion layer thickness.
A T, Lu, M E, Frisella, K C, Johnson
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Dissolution Rate Studies on Methylprednisolone Polymorphs

Journal of Pharmaceutical Sciences, 1964
Dissolution rates (DR) of methylprednisolone polymorphs I and II were determined by the rotating disk method as a function of rate of rotation (RR). The results show that the DR-RR relationship differs from that normally expected in the case of diffusion-controlled dissolution from rotating disks.
G, LEVY, J A, PROCKNAL
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