Dissolution enhancement of gliclazide using pH change approach in presence of twelve stabilizers with various physico-chemical properties [PDF]
, 2009 Purpose. The micronization using milling process to enhance dissolution rate is extremely inefficient due to a high energy input, and disruptions in the crystal lattice which can cause physical or chemical instability.
Mostafavi, Seyed Abolfazl +3 more
core +2 more sources
Environmental Science and Technology, 2019 The objectives of this research were to quantify the impact of organic matter content, soil pH and moisture content on the dissolution rate and solubility of copper oxide nanoparticles (CuO NPs) in soil, and to develop an empirical model to predict the ...
Xiaoyu Gao +10 more
semanticscholar +1 more source
Addition of Sodium Bicarbonate to Irrigation Solution May Assist in Dissolution of Uric Acid Fragments During Ureteroscopy [PDF]
, 2018 Introduction: We hypothesized that adding sodium bicarbonate (bicarb) to normal saline (NS) irrigation during ureteroscopy in patients with uric acid (UA) nephrolithiasis may assist in dissolving small stone fragments produced during laser lithotripsy ...
Lingeman, James E. +2 more
core +1 more source
Dissolution dominating calcification process in polar pteropods close to the point of aragonite undersaturation [PDF]
, 2014 Thecosome pteropods are abundant upper-ocean zooplankton that build aragonite shells. Ocean acidification results in the lowering of aragonite saturation levels in the surface layers, and several incubation studies have shown that rates of calcification ...
AG Dickson +57 more
core +3 more sources
Pharmaceutics, 2021 The effectiveness of oral drug administration is related to the solubility of a drug in the gastrointestinal tract and its ability to penetrate the biological membranes. As most new drugs are poorly soluble in water, there is a need to develop novel drug
Adrianna Dadej +8 more
doaj +1 more source
Dissolution Kinetics of Meloxicam Formulations Co-Milled with Sodium Lauryl Sulfate
Pharmaceutics, 2022 Meloxicam (MLX) is a poorly soluble drug exhibiting strong hydrophobicity. This combination of properties makes dissolution enhancement by particle size reduction ineffective; therefore, combined formulation approaches are required.
Jan Patera +2 more
doaj +1 more source
Impacts of glass composition, pH, and temperature on glass forward dissolution rate
npj Materials Degradation, 2018 Nuclear waste glasses dissolve at the forward dissolution rate (rf) in very dilute aqueous solutions, which can isolate the impact of the glass composition from solution feedback and alteration product effects.
J. Vienna +3 more
semanticscholar +1 more source
Dissolution Profile of Nimesulide from Pharmaceutical Preparations for Oral Use
Acta Chimica Slovenica, 2016 Nimesulide belongs to the group of semi-selective COX-2 inhibitors, widely used in solid oral formulations. In the present work the influence of surfactants among other drug excipients, as well as particle size of the active substance and the effects of ...
Biljana Tubić +3 more
doaj +1 more source
Surface‐Volume Scaling Controlled by Dissolution Regimes in a Multiphase Flow Environment
Geophysical Research Letters, 2023 Fluid‐rock dissolution occurs ubiquitously in geological systems. Surface‐volume scaling is central to predicting overall dissolution rate R involved in modeling dissolution processes.
Chen‐Xing Zhou +5 more
doaj +1 more source
Albendazole Solid Dispersions: Influence of Dissolution Medium Composition on In Vitro Drug Release [PDF]
, 2014 The rate-limiting step to drug absorption is often dissolution from the dosage form, especially for poorly soluble com-pounds. Two possibilities for improving the dissolution of these drugs are to increase the available surface area and to im-prove their
Allemandi, Daniel Alberto +4 more
core +1 more source