Results 111 to 120 of about 475,693 (306)
FEBS Open Bio, EarlyView.Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata +13 more
wiley +1 more source
SCIENTIFIC-METHODICAL APPROACHES AND RESULTS OF THE PHARMACEUTICAL DEVELOPMENT OF SUPPOSITORIES
Разработка и регистрация лекарственных средств, 2019 In article theoretical and practical results of longstanding work of collective of Pharmaceutical technology department of Kursk State Medical University for the development of rectal and vaginal suppositories for the treatment of infectious and ...
T. A. Pankrusheva +4 more
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Development and Application of Carbonate Dissolution Test Equipment under Thermal-Hydraulic-Chemical Coupling Condition. [PDF]
Materials (Basel), 2022 Meng J, Chen S, Wang J, Chen Z, Zhang J.
europepmc +1 more source
, 2021 This dissertation explores the concept of Real Time Release applied to the dissolution of tablets. The goal is to propose an alternative appropriate quality control strategy for medicine, whose pharmaceutical formulation is a film-coated tablet containing active ibuprofen, through the analysis of the ICH Q6A guideline and other regulatory concepts. The
openaire +1 more source
D 5.4.1.3. Final Report on sensory testing in Europe for Group 3. Project AFTER “African Food Tradition rEvisited by Research” [PDF]
, 2015 The work presented in this deliverable had as main objective the sensory profiling of products resulting from process reengineering of traditional products from group 3 − plant based extracts.
Bechoff, Aurélie +10 more
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FEBS Open Bio, EarlyView.Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar +4 more
wiley +1 more source
Long-term stability of clopidogrel solid dispersions-Importance of in vitro dissolution test. [PDF]
PLoS One, 2022 Osmanović Omerdić E +6 more
europepmc +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
Preparation and characterization of silymarin synchronized-release microporous osmotic pump tablets
Drug Design, Development and Therapy, 2016 Qi-ping Zeng,* Zhi-hong Liu,* Ai-wen Huang, Jing Zhang, Hong-tao Song Department of Pharmacy, Fuzhou General Hospital of Nanjing Command PLA, Fuzhou, People’s Republic of China *These authors contributed equally to this work Abstract: The ...
Zeng QP +4 more
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